Arthritis & Rheumatology recently published findings from the Johnston County Health Study (), led by Amanda Nelson, MD, MSCR, RhMSUS, Professor of Medicine in the Division of Rheumatology, Allergy & Immunology at 黑料网, revealing significant associations between ultrasound (US) features and knee osteoarthritis (KOA). The investigators also demonstrated the diagnostic accuracy of US definitions for radiographic KOA.
Several TARC researchers contributed to the work, including Yvonne Golightly PT PhD, Tessa Walker MPH, Sue Guin RT(R), Jordan Renner MD, Todd Schwartz DrPH, Carolina Alvarez MS, and lead author and former fellow (now on faculty at Ohio State), along with researchers from other institutions, including several members of the Ultrasound School of North American Rheumatologists ().
This study utilized the group鈥檚 previously protocol and atlas to generate and score standardized US features in a community-based cohort of Black, White, and Hispanic men and women with and without OA. Through their participation in the JoCoHS, all of these individuals completed numerous questionnaires regarding various aspects of their health along with standardized radiographs and US. This unique dataset allowed the study team to determine associations among US features and important KOA outcomes, while demonstrating the utility, reliability, and accessibility of US in OA.
To learn more about this study, read the or the attached abstract.
Yates KA, Alvarez C, Schwartz TA, Savage-Guin S, Renner JB, Bakewell CJ, Kohler MJ, Lin J, Samuels J, Walker T, Golightly YM, Nelson AE. Associations and Diagnostic Accuracy of Ultrasound Features in Knee Osteoarthritis: Cross-sectional Results from a Large Community-based Cohort. Arthritis Rheumatol. 2025 Feb 24. doi: 10.1002/art.43139. Epub ahead of print. PMID: 39989271.