{"id":12020,"date":"2019-11-12T14:36:33","date_gmt":"2019-11-12T19:36:33","guid":{"rendered":"https:\/\/www.med.unc.edu\/pharm\/?post_type=directory&#038;p=12020"},"modified":"2024-08-12T10:35:39","modified_gmt":"2024-08-12T14:35:39","slug":"greg-scherrer-phd","status":"publish","type":"directory","link":"https:\/\/www.med.unc.edu\/pharm\/directory\/greg-scherrer-phd\/","title":{"rendered":"Greg Scherrer, PhD"},"content":{"rendered":"<h2><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-11601\" src=\"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2019\/01\/OGE-Trained-mentor-badge-webCR2-300x204.png\" alt=\"\" width=\"300\" height=\"204\" srcset=\"https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2019\/01\/OGE-Trained-mentor-badge-webCR2-300x204.png 300w, https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2019\/01\/OGE-Trained-mentor-badge-webCR2-768x522.png 768w, https:\/\/www.med.unc.edu\/pharm\/wp-content\/uploads\/sites\/930\/2019\/01\/OGE-Trained-mentor-badge-webCR2-1024x696.png 1024w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/h2>\n<h2>Research Interests<\/h2>\n<ul>\n<li>Pain and Opioids<\/li>\n<\/ul>\n<h2>Research Synopsis<\/h2>\n<p>Pain and Opioids. Pain is a complex and multidimensional experience with sensory and emotional components. The members of the\u00a0<strong>Scherrer Lab<\/strong>\u00a0aim to elucidate the mechanisms by which our nervous system generates the different dimensions of pain experience, at the genetic, molecular, cellular, neural circuit, and behavioral levels, using the mouse as a model system. We also seek to resolve the mechanisms of action of opioids and understand how these drugs alter activity in neural circuits to produce analgesia, but also deleterious side effects such as tolerance, addiction and respiratory depression. To this aim, we investigate the functional organization of our endogenous opioid system and the localization, trafficking and signaling properties of opioid receptors in neurons\u00a0<em>in vivo<\/em>. Collectively, these studies expand our understanding of pain neurobiology and the mechanisms of action of opioids to develop solutions against chronic pain and the opioid epidemic, by identifying novel non-addictive drug targets to treat pain and strategies to disassociate opioid analgesia from side effects.<\/p>\n<h2>Publications<\/h2>\n<p><strong><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/myncbi\/gregory.scherrer.1\/bibliography\/public\/\" rel=\"noopener noreferrer\">View complete list of publications in NCBI library<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Research Interests Pain and Opioids Research Synopsis Pain and Opioids. Pain is a complex and multidimensional experience with sensory and emotional components. The members of the\u00a0Scherrer Lab\u00a0aim to elucidate the mechanisms by which our nervous system generates the different dimensions of pain experience, at the genetic, molecular, cellular, neural circuit, and behavioral levels, using the &hellip; <a href=\"https:\/\/www.med.unc.edu\/pharm\/directory\/greg-scherrer-phd\/\" aria-label=\"Read more about Greg Scherrer, PhD\">Read more<\/a><\/p>\n","protected":false},"featured_media":18472,"template":"","meta":{"_acf_changed":false,"_links_to":"","_links_to_target":""},"class_list":["post-12020","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Greg Scherrer, PhD | Pharmacology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/pharm\/directory\/greg-scherrer-phd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Greg Scherrer, PhD | Pharmacology\" \/>\n<meta property=\"og:description\" content=\"Research Interests Pain and Opioids Research Synopsis Pain and Opioids. 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Physiology\r\n<\/strong><span style=\"background-color: #007fae;color: #fff\">Accepting Rotation Students<\/span>\r\nResearch: Pain and opioids\r\nOffice: 6008B MEJ\r\nPhone: <a href=\"tel:+19198438624\">919-843-8624<\/a>\r\n<a href=\"https:\/\/www.scherrerlab.com\/\" rel=\"noopener\">Lab Website<\/a>\r\n<a href=\"mailto:gregory_scherrer@med.unc.edu\">Email<\/a>"],"_upd_no_link":[],"_upd_degree1":["PhD"],"_upd_degree2":[],"_upd_email":[[{"email_text":"gregory_scherrer@med.unc.edu"}]],"_upd_phone":[[{"phone_text":"(919) 843-8624","phone_type":"Office Phone"}]],"_upd_address":[[{"address":{"address-1":"116 Manning Dr.","address-2":"6008B Mary Ellen Jones Bld","campus-box":"CB# 7250","city":"Chapel Hill","state":"NC","zip":"27599"}}]],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/directory\/12020","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/directory"}],"about":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/types\/directory"}],"version-history":[{"count":5,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/directory\/12020\/revisions"}],"predecessor-version":[{"id":18358,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/directory\/12020\/revisions\/18358"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/media\/18472"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/pharm\/wp-json\/wp\/v2\/media?parent=12020"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}