BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Pharmacology - ECPv6.11.1//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-ORIGINAL-URL:/pharm X-WR-CALDESC:Events for Pharmacology REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:America/New_York BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20250309T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20251102T060000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=America/New_York:20250304T160000 DTEND;TZID=America/New_York:20250304T170000 DTSTAMP:20250530T214850 CREATED:20250114T202148Z LAST-MODIFIED:20250114T203325Z UID:10000986-1741104000-1741107600@www.med.unc.edu SUMMARY:Dr. Kate White of the University of Southern California presents DESCRIPTION:Kate White\, PhD\nGabilan Assistant Professor of Chemistry\nDepartment of Chemistry\nUniversity of Southern California \nSeminar Title:聽鈥淐hemical biology approaches for mapping peptide hormone maturation鈥� \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to聽Mimi Baltz.) \nHost: Rob Nicholas\n \nDr. White studies secretion in pancreatic beta cells and neuron and is a former postdoc of the Nicholas and Roth Labs. \n鈥淥ur lab focuses on developing new chemical biology tools to uncover how cells coordinate the secretion of peptide hormones鈥攕mall chains of amino acids that circulate in the blood and bind to specific cell receptors. Defects in the storage\, maturation (enzymatic cleavage)\, or secretion of these hormones can lead to various mental and metabolic disorders\, including depression\, bipolar disorder\, and diabetes. Using pancreatic 尾-cells and neurons as model systems\, we investigate how these cells reorganize during peptide hormone production\, trafficking\, and secretion. Despite the critical role of this secretion mechanism\, the cellular signals regulating secretory vesicle maturation are still unclear. To address this knowledge gap\, our lab has four main research directions:聽 \n\n\nDefine signaling pathways that regulate peptide hormone maturation. \n\n\nInvestigate the biochemical role of inter-organelle communication in regulating secretory systems. \n\n\nExamine the biochemical role of cellular and organelle subtypes in secretory cells. \n\n\nDevelop community-based tools to support the next generation of cellular modeling.鈥� \n\n\n~ https://www.katewhitelab.com/ \nFlyer [pdf] URL:/pharm/event/dr-kate-white-of-the-university-of-southern-california-presents/ LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States CATEGORIES:Pharmacology Seminars ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/01/Kate_White_USC-250.jpg ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu END:VEVENT END:VCALENDAR