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X-WR-CALDESC:Events for Pharmacology
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TZID:America/New_York
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DTSTART:20250309T070000
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250304T160000
DTEND;TZID=America/New_York:20250304T170000
DTSTAMP:20250428T144322
CREATED:20250114T202148Z
LAST-MODIFIED:20250114T203325Z
UID:10000986-1741104000-1741107600@www.med.unc.edu
SUMMARY:Dr. Kate White of the University of Southern California presents
DESCRIPTION:Kate White\, PhD\nGabilan Assistant Professor of Chemistry\nDepartment of Chemistry\nUniversity of Southern California \nSeminar Title: “Chemical biology approaches for mapping peptide hormone maturation” \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHost: Rob Nicholas\n \nDr. White studies secretion in pancreatic beta cells and neuron and is a former postdoc of the Nicholas and Roth Labs. \n“Our lab focuses on developing new chemical biology tools to uncover how cells coordinate the secretion of peptide hormones—small chains of amino acids that circulate in the blood and bind to specific cell receptors. Defects in the storage\, maturation (enzymatic cleavage)\, or secretion of these hormones can lead to various mental and metabolic disorders\, including depression\, bipolar disorder\, and diabetes. Using pancreatic β-cells and neurons as model systems\, we investigate how these cells reorganize during peptide hormone production\, trafficking\, and secretion. Despite the critical role of this secretion mechanism\, the cellular signals regulating secretory vesicle maturation are still unclear. To address this knowledge gap\, our lab has four main research directions:  \n\n\nDefine signaling pathways that regulate peptide hormone maturation. \n\n\nInvestigate the biochemical role of inter-organelle communication in regulating secretory systems. \n\n\nExamine the biochemical role of cellular and organelle subtypes in secretory cells. \n\n\nDevelop community-based tools to support the next generation of cellular modeling.” \n\n\n~ https://www.katewhitelab.com/ \nFlyer [pdf]
URL:/pharm/event/dr-kate-white-of-the-university-of-southern-california-presents/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/01/Kate_White_USC-250.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250311T160000
DTEND;TZID=America/New_York:20250311T170000
DTSTAMP:20250428T144322
CREATED:20250217T201108Z
LAST-MODIFIED:20250217T201108Z
UID:10000995-1741708800-1741712400@www.med.unc.edu
SUMMARY:Dr. Gerald Shadel of the Salk Institute for Biological Sciences presents
DESCRIPTION:Gerald Shadel\, PhD\nProfessor\nMolecular and Cell Biology Laboratory\nAudrey Geisel Chair in Biomedical Science\nDirector\, San Diego-Nathan Shock Center of Excellence in the Basic Biology of Aging\nSalk Institute for Biological Studies \nSeminar title: “Mitochondrial Signaling in Aging\, Disease and Immunity” \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHost: Lee Graves \n“Gerald Shadel studies the basic biology of mitochondria and mtDNA\, and\, in doing so\, has identified novel ways that mitochondria contribute to disease\, aging and the immunesystem. He is also interested in understanding how mitochondria are involved in cellular signaling processes. He seeks to identify what the signals are\, what pathways they trigger and how they play a part in aging\, cancer and metabolic and degenerative diseases. His group takes a multidisciplinary view\, exploring mitochondrial function—and dysfunction—via cultured cells\, model organisms and other genetic and biochemical approaches.” \n~ https://www.salk.edu/scientist/gerald-shadel/\nLab website: https://shadel.salk.edu/ \nFlyer [pdf]
URL:/pharm/event/dr-gerald-shadel-of-the-salk-institute-for-biological-sciences-presents/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/01/gerald-shadel-250-2.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250318T160000
DTEND;TZID=America/New_York:20250318T170000
DTSTAMP:20250428T144322
CREATED:20250312T140829Z
LAST-MODIFIED:20250312T141650Z
UID:10001001-1742313600-1742317200@www.med.unc.edu
SUMMARY:POSTPONED - Dr. Kenneth A. Jacobson from the National Institutes of Health presents
DESCRIPTION:Kenneth A. Jacobson\, PhD\nJohn W. Daly Distinguished Scientist\nSenior Investigator\nLaboratory of Bioorganic Chemistry\nNIDDK\, National Institutes of Health \nSeminar Title: “Action of Nucleosides and Nucleotides at Purinergic and Non-Purinergic Drug Targets” \nTHIS SEMINAR HAS BEEN POSTPONED \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHost: Yinglong Miao \nDr. Jacobson is an established medicinal chemist with interests in the structure and pharmacology of receptors and in developing drugs that act as agonists or antagonists of G protein-coupled receptors (GPCRs). His current focus is on receptors for purines\, encompassing both adenosine receptors and P2 receptors\, which are activated by ATP\, UTP and other extracellular nucleotides. His lab has taken an interdisciplinary approach to studying the chemical and biological aspects of these receptors. They have used convergent modeling\, mutagenesis and structure activity approaches to gather information about the three-dimensional structure of the receptors and its relationship to binding and activation functions. \nhttps://www.niddk.nih.gov/about-niddk/staff-directory/biography/jacobson-kenneth \nFlyer [pdf]
URL:/pharm/event/dr-kenneth-a-jacobson-from-the-national-institutes-of-health-presents/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2024/12/Jacobson-Kenneth_250x250.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250321T110000
DTEND;TZID=America/New_York:20250321T120000
DTSTAMP:20250428T144322
CREATED:20250319T143726Z
LAST-MODIFIED:20250319T143726Z
UID:10001003-1742554800-1742558400@www.med.unc.edu
SUMMARY:Student Research Seminars with Kyle Pellegrino\, Lizzy Obarow and Grace Stroman
DESCRIPTION:Kyle Pellegrino\, Cohen Lab\nLizzy Obarow\, Dohlman Lab\nGrace Stroman\, Pruitt Lab \nHosted by Kalynn Van Voorhies\, Kash Lab \nLocation: 4007 GMB \nPizza at 12:00 PM\, following seminar for attendees \nFlyer [pdf]
URL:/pharm/event/student-research-seminars-with-kyle-pellegrino-lizzy-obarow-and-grace-stroman/
LOCATION:4007 Genetic Medicine Building\, 120 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Student Research Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/02/2025_03_21_Pellegrino_Obarow_Stroman.jpg
ORGANIZER;CN="April Villaneuva":MAILTO:april_villanueva@med.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250325T160000
DTEND;TZID=America/New_York:20250325T170000
DTSTAMP:20250428T144322
CREATED:20250310T204042Z
LAST-MODIFIED:20250310T204133Z
UID:10001000-1742918400-1742922000@www.med.unc.edu
SUMMARY:Dr. Megan Agajanian of Stanford presents
DESCRIPTION:Megan Agajanian\, PhD\nPostdoctoral Scholar\, Roel Nuuse Lab\nDepartment of Developmental Biology\nStanford University \nSeminar title: “The dynamic role of TBX3 in “The dynamic role of TBX3 in cancer and development” \nLocation: 1131 Bioinformatics \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHost: Mike Emanuele \nMegan is a postdoc in Roul Nouse’s lab\, the person who first identified Wnt signaling in humans. She is a former Pharmacology student in the Emanuele Lab.  She has been funded by HHMI Gilliam and a K00 Award\, and was selected for the NSF-ASCB FRED Program. \nDr. Agajanian is interested in lineage plasticity and the signals that drive diverse cellular responses. Her postdoctoral work focuses on the dynamic role of TBX3 in breast cancer and mammary gland development. TBX3 mutations in the developing embryo result in Ulnar Mammary Syndrome\, which is characterized by incomplete mammary gland development. In contrast\, TBX3 is mutated in breast cancer and is associated with metastasis. Despite these critical roles of TBX3\, the role of patient mutations in breast cancer progression and the role of TBX3 in postnatal mammary gland expansion remain virtually unstudied. Using organoid and mouse models\, we have demonstrated TBX3 supports organoid growth and in vivo is required for mammary gland expansion during puberty. Interestingly\, previous work identified TBX3 as a lineage specific component of the Wnt transcriptional complex in colorectal cancer\, but it’s role in Wnt signaling in the mammary gland remains unknown. With her background in Wnt signaling interrogation\, in the future\, she aims to pursue her interest in lineage and context dependent regulators of this critical signaling cascade using a wide array of techniques\, including organoid models\, molecular biology\, proteomic\, and in vivo approaches. \n“My project focuses on TBX3 (T-Box Transcription Factor 3)\, one of the top ten mutated genes in breast cancer. TBX3 upregulation and loss of function mutations are identified in patients\, raising the question: is TBX3 a proto-oncogene or tumor suppressor? My work in the Nusse lab will define the role of TBX3 in breast cancer progression and identify TBX3 targets that can be utilized as therapeutic targets in TBX3-associated breast cancer.” ~ https://nusselab.stanford.edu/people/megan-agajanian/ \nFlyer [pdf]
URL:/pharm/event/dr-megan-agajanian-of-stanford-presents/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/01/megan-agajanian-250.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250328T110000
DTEND;TZID=America/New_York:20250328T120000
DTSTAMP:20250428T144322
CREATED:20250327T154510Z
LAST-MODIFIED:20250327T154510Z
UID:10001005-1743159600-1743163200@www.med.unc.edu
SUMMARY:Student Research Seminars with Scott Bang\, Amy Aponte and Ryan Robb
DESCRIPTION:Scott Bang\, Morris Lab\nAmy Aponte\, Emanuele Lab\nRyan Robb\, Bryant Lab \nHosted by Emma Armstrong\, Morris Lab \nLocation: 4007 GMB \nPizza at 12:00 PM\, following seminar for attendees \nFlyer [pdf]
URL:/pharm/event/student-research-seminars-with-scott-bang-amy-aponte-and-ryan-robb/
LOCATION:4007 Genetic Medicine Building\, 120 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Student Research Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/03/2025_03_28_student_seminar_flyer_Bang_Aponte_Robb.jpg
ORGANIZER;CN="April Villaneuva":MAILTO:april_villanueva@med.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250401T160000
DTEND;TZID=America/New_York:20250401T170000
DTSTAMP:20250428T144322
CREATED:20250326T180048Z
LAST-MODIFIED:20250326T180048Z
UID:10001004-1743523200-1743526800@www.med.unc.edu
SUMMARY:Dr. Terry Kenakin of ������-CH presents
DESCRIPTION:Terry Kenakin\, PhD\nProfessor and Course Coordinator\nDepartment of Pharmacology\nUniversity of North Carolina at Chapel Hill \nTitle of Talk: “A Renaissance in GPCRs – Allosterism and Biased Agonism in Drug Discover” \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHost: Henrik Dohlman \nDr. Kenakin will present about signaling bias and allostery in GPCRs and how it has transformed GPCR drug discovery over the past 15 years. \nFlyer [pdf] \n \n 
URL:/pharm/event/dr-terry-kenakin-of-unc-ch-presents/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/02/TKenakin-15-250.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250408T160000
DTEND;TZID=America/New_York:20250408T170000
DTSTAMP:20250428T144322
CREATED:20250401T200939Z
LAST-MODIFIED:20250401T200939Z
UID:10001007-1744128000-1744131600@www.med.unc.edu
SUMMARY:Dr. Brian Krumm of ������-CH presents
DESCRIPTION:Brian Krumm\, PhD\nAssistant Professor\nDepartment of Pharmacology\nUniversity of North Carolina at Chapel Hill \nSeminar title: “Biased Allosteric Modulators and the Neurotensin Receptor: The Quest for Precision Pharmacology” \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHost: Henrik Dohlman \nDr. Krumm’s research is focused on understanding the integral membrane proteins\, specifically the G Protein Coupled Receptor (GPCR).  A member of the Roth lab\, he helped to successfully facilitate the structural determination of multiple GPCRs including the first crystal structure of the active-state kappa opioid receptor in complex with state-distinct nanobody along with the crystal structure of the serotonin 5-HT2A GPCR and the Cryo-Em structure of this receptor and other GPCRs in complex with its cognate G-protein. \nMost recently he was co-first author on this important paper published Dec. 26\, 2024 in Cell\, “Structure-guided design of a peripherally restricted chemogenetic system\,” which describes the development of a groundbreaking molecular technology to reduce pain by targeting peripheral nervous system (PNS) nociceptors. \n~ /pharm/directory/brian-krumm/ \nFlyer [pdf]
URL:/pharm/event/dr-brian-krumm-of-unc-ch-presents/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2019/04/Brian-Krumm-250-2.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250411T110000
DTEND;TZID=America/New_York:20250411T120000
DTSTAMP:20250428T144322
CREATED:20250407T184207Z
LAST-MODIFIED:20250407T184207Z
UID:10001008-1744369200-1744372800@www.med.unc.edu
SUMMARY:Student Research Seminars with Maddy Jenner\, Tania Bellinger and Anthony Hazelton
DESCRIPTION:Maddy Jenner\, Yeh/Gomez Labs\nTania Bellinger\, Reissner Lab\nAnthony Hazelton\, Nguyen Lab \nHosted by Alex Brown\, McElligott Lab \nLocation: 4007 GMB \nPizza at 12:00 PM\, following seminar for attendees \nFlyer [Pdf]
URL:/pharm/event/student-research-seminars-with-maddy-jenner-tania-bellinger-and-anthony-hazelton/
LOCATION:4007 Genetic Medicine Building\, 120 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Student Research Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/02/2025_04_11-Student-seminars-Jenner-Bellinger-Hazelton.jpg
ORGANIZER;CN="April Villaneuva":MAILTO:april_villanueva@med.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250415T160000
DTEND;TZID=America/New_York:20250415T170000
DTSTAMP:20250428T144322
CREATED:20250109T153745Z
LAST-MODIFIED:20250401T211612Z
UID:10000983-1744732800-1744736400@www.med.unc.edu
SUMMARY:Dr. Mauro Calabrese of ������-CH presents
DESCRIPTION:Mauro Calabrese\, PhD\nAssociate Professor\nDepartment of Pharmacology\nUniversity of North Carolina at Chapel Hill \nSeminar title: “Mechanisms of gene silencing by long noncoding RNAs” \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHost: Henrik Dohlman \n“The Calabrese lab studies how long noncoding RNAs (lncRNAs) regulate gene expression. We are particularly interested in understanding the relationships between sequence\, structure\, and function in lncRNAs\, as well as the mechanisms that lncRNAs employ to control molecular events inside of the nucleus.”\n~ /pharm/calabreselab/ \nFlyer [pdf]
URL:/pharm/event/dr-mauro-calabrese-of-unc-ch-presents/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/01/Mauro-Calabrese-927-2023-400-2-250.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250425T110000
DTEND;TZID=America/New_York:20250425T120000
DTSTAMP:20250428T144322
CREATED:20250421T184528Z
LAST-MODIFIED:20250421T184528Z
UID:10001010-1745578800-1745582400@www.med.unc.edu
SUMMARY:Student Research Seminars with Brandon Pratt and Runfan Yang
DESCRIPTION:Brandon Pratt\, Milner Lab\nRunfan Yang\, Sondek Lab \nHosted by Sarah Ackermann\, Bryant Lab \nLocation: 4007 GMB \nPizza at 12:00 PM\, following seminar for attendees \nFlyer [pdf]
URL:/pharm/event/student-research-seminars-with-brandon-pratt-and-runfan-yang/
LOCATION:4007 Genetic Medicine Building\, 120 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Student Research Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/03/2025_04_25-Student-seminars-Pratt-Yang-Flyer-1000.jpg
ORGANIZER;CN="April Villaneuva":MAILTO:april_villanueva@med.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250604T153000
DTEND;TZID=America/New_York:20250604T164500
DTSTAMP:20250428T144322
CREATED:20250411T141112Z
LAST-MODIFIED:20250411T145046Z
UID:10001009-1749051000-1749055500@www.med.unc.edu
SUMMARY:5th Annual Dr. Curtis Harper Distinguished Lectureship & Celebration Featuring Dr. Kizzmekia Corbett-Helaire of Harvard University
DESCRIPTION:Kizzmekia Corbett-Helaire\, Ph.D.\nMelvin J. & Geraldine L. Glimcher\nAssistant Professor\nImmunology and Infectious Diseases\nHarvard T.H. Chan School of Public Health \nLecture Title: “Using Viral Immunology to Inform Universal Coronavirus Virus Development”\n \nTime: 3:30 PM (Followed by a Reception @ 5PM)\nLocation: 2204 MBRB (Medical Biomolecular Research Bldg)\nHosted by: The Curtis Harper Planning Committee (Chair: Dr. Antonio ‘Tony’ Baines) & ������ Pharmacology Department \nWe are honored to welcome Dr. Kizzmekia Corbett-Helaire\, as this year’s keynote speaker. Dr. Corbett-Helaire\, a distinguished alumna of ������-Chapel Hill\, earned her Ph.D. in Microbiology & Immunology in 2014. She is widely recognized for her groundbreaking role as the leader of the NIH team that developed the Moderna COVID-19 Vaccine. \nHer keynote presentation\, titled “Using Viral Immunology to Inform Universal Coronavirus Virus Development”\, promises to be an inspiring and informative session. \nCome out & join us to show your support! \nFlyer [pdf]
URL:/pharm/event/5th-annual-dr-curtis-harper-distinguished-lectureship-celebration-featuring-dr-kizzmekia-corbett-helaire-harvard/
LOCATION:2204 MBRB (Molecular Biomedical Research Building)\, 111 Mason Farm Rd.\, Chapel Hill\, NC\, 27599
CATEGORIES:Special Events
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/04/2025-Curtis-Harper-Flyer.jpg
ORGANIZER;CN="Jess Tran":MAILTO:jesstran@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250909T160000
DTEND;TZID=America/New_York:20250909T170000
DTSTAMP:20250428T144322
CREATED:20240611T151411Z
LAST-MODIFIED:20240611T151411Z
UID:10000953-1757433600-1757437200@www.med.unc.edu
SUMMARY:Fall Steelman Distinguished Lecturer\, Lisa M. Coussens of Oregon Health & Science University presents
DESCRIPTION:Lisa M. Coussens\, Ph.D.\, FAACR\, FAIO\nHildegard Lamfrom Endowed Chair in Basic Science\nProfessor and Chairwoman\, Department of Cell\, Developmental & Cancer Biology\nDeputy Director for Basic & Translational Research\, Knight Cancer Institute\nOregon Health & Science University \nSeminar title: TBD \nThis seminar will be in 1131 Bioinformatics \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHost: Steelman Committee (Mike Emanuele\, Kirsten Bryant\, Kevin Pruitt\, John Morris) \nAbout Dr. Coussens’ research: The Coussen’s lab is “interested in understanding the molecular and cellular mechanisms that regulate leukocyte recruitment into neoplastic tissue\, and the subsequent regulation those leukocytes exert on evolving cancer cells.” ~ Coussen’s Lab website
URL:/pharm/event/fall-steelman-distinguished-lecturer-lisa-m-coussens-of-oregon-health-science-univeristy-presents/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2024/06/Lisa-Coussens-250-3.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250916T160000
DTEND;TZID=America/New_York:20250916T170000
DTSTAMP:20250428T144322
CREATED:20250108T202503Z
LAST-MODIFIED:20250108T202503Z
UID:10000980-1758038400-1758042000@www.med.unc.edu
SUMMARY:Dr. Kim Green of the University of California\, Irvine presents
DESCRIPTION:Kim Green\, PhD\nProfessor\nDepartment of Neurobiology and Behavior\nUniversity of California\, Irvine \nSeminar title: “TBD” \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHost: Leon Coleman \nDr. Green has been a pioneer in two areas in the Alzheimer’s/neurobiology research field: \n1) He has made pioneering discoveries regarding the role of microglia in Alzheimer’s disease and healthy neurobiology. He has made many contributions\, including identifying the colony stimulated factor receptor 1 (CSFR1) as a required receptor for microglial survival. Currently CSFR1 antagonists are broadly used in the field to study the impacts of microglial depletion on brain function. \n2) The development of mouse models for Alzheimer’s disease. Dr. Green is a PI of the MODEL-AD consortium\, which has developed many of the most widely used mouse models for Alzheimer’s disease. The MODEL-AD consortium has also recently developed mouse models for late onset/sporadic AD\, which will be invaluable for the field. \n~ https://faculty.sites.uci.edu/kimgreen \n 
URL:/pharm/event/dr-kim-green-of-the-university-of-california-irvine-presents/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/01/IMG_7771_Kim_Green-250.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250930T160000
DTEND;TZID=America/New_York:20250930T170000
DTSTAMP:20250428T144322
CREATED:20250428T135117Z
LAST-MODIFIED:20250428T135117Z
UID:10001012-1759248000-1759251600@www.med.unc.edu
SUMMARY:Dr. Shaun Olsen of the University of Texas San Antonio presents
DESCRIPTION:Shaun Olsen\, PhD\nProfessor\nDepartment of Biochemistry & Structural Biology\nUniversity of Texas\, San Antonio \nSeminar title: TBD \nThis seminar will be in 1131 Bioinformatics \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHost: Rob Nicholas \n  \nThe research in the Olsen laboratory focuses on mechanisms of molecular recognition in protein-protein interactions and on the structural enzymology of proteins essential for cellular function. The majority of his efforts are focused on understanding how enzymes in the ubiquitin (Ub) conjugation cascade (E1\, E2\, and E3) function together to conjugate Ub to cellular proteins. Post-translational modification of proteins by Ub is a means of regulating fundamental cellular processes including cell cycle control\, DNA repair\, signal transduction\, and immunity. The importance of understanding how the Ub system works is underscored by the fact that dysregulation of Ub signaling is implicated in a number of human disorders and that the pathway is a validated target for therapeutic intervention in cancer. He employs a multidisciplinary approach that includes X-ray crystallography\, single particle cryo-EM\, enzymology\, and a variety of biochemical and biophysical techniques. (from his web site-  ~https://directory.uthscsa.edu/academics/profile/olsens)
URL:/pharm/event/dr-shaun-olsen-of-the-university-of-texas-san-antonio-presents/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/04/olsen_shaun_250.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20251007T160000
DTEND;TZID=America/New_York:20251007T170000
DTSTAMP:20250428T144322
CREATED:20250106T212053Z
LAST-MODIFIED:20250106T212346Z
UID:10000977-1759852800-1759856400@www.med.unc.edu
SUMMARY:Dr. Sara Buhrlage of the Dana-Farber Cancer Institute presents
DESCRIPTION:Sara Buhrlage\, PhD\nAssociate Professor\nDepartment of Biological Chemistry and Molecular Pharmacology\nHarvard University Medical School and the\nDana-Farber Cancer Institute \nSeminar Title: “TBD” \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHosts: Mike Emanuele and Nick Brown \nFrom the Buhrlage Lab website: “Our mission is to revolutionize our ability to interrogate deubiquitinase (DUB) biology\, validate DUBs as therapeutic targets\, and develop small molecule-based ligands suitable for clinical development. To accomplish this\, we have established an integrated DUB-centric platform comprised of DUB-targeted libraries with novel scaffolds and chemotypes and a suite of established and novel biochemical and chemoproteomic assays to profile compound activity and selectivity\, as well as expertise in DUB medicinal chemistry\, structural biology\, computational chemistry\, and functional annotation.” ~ https://buhrlagelab.dana-farber.org/
URL:/pharm/event/dr-sara-buhrlage-of-the-dana-farber-cancer-institute-presents/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/01/7884248-Sara-Buhrlage-250.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20251014T160000
DTEND;TZID=America/New_York:20251014T170000
DTSTAMP:20250428T144322
CREATED:20250428T141414Z
LAST-MODIFIED:20250428T141414Z
UID:10001013-1760457600-1760461200@www.med.unc.edu
SUMMARY:Dr. Marta Filizola
DESCRIPTION:Marta Filizola\, PhD\nProfessor of Pharmacological Sciences and Neuroscience\nDean of the Graduate School of Biomedical Sciences\nIcahn School of Medicine at Mount Sinai\n\nSeminar title: TBD\n\nThis seminar will be in 1131 Bioinformatics\n\nPlease join us and show support for our seminar speakers!\n\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHost: Yinglong Miao \n\n  \nFrom the Filizola website: Our research program aims to obtain rigorous mechanistic insights into the structure\, dynamics\, and function of important classes of membrane proteins and prominent drug targets\, including G protein-coupled receptors (GPCRs)\, transporters\, channels\, and beta3 integrins. Understanding the molecular mechanisms underlying the complex biological functions of these proteins has direct translational relevance because it informs the rational discovery of potentially improved therapeutic agents. To this end\, we use several computational structural biology tools and rational drug design approaches\, ranging from molecular modeling\, bioinformatics\, cheminformatics\, molecular dynamics simulations\, metadynamics\, free-energy perturbations\, artificial intelligence/machine learning\, etc. \nThe strength of our research relies on the integration of state-of-the-art computational methodologies with collaborative experimental approaches to provide valuable mechanistic interpretations at the molecular level of the ligand-induced transmission of the signal to the inner side of the cell membrane. While our research is driven by the exploration and improvement of computational methods to characterize generalizable mechanisms of molecular recognition and signal transduction\, we are excited by the contributions that our computational and modeling efforts make to the experimental field through the generation of new testable hypotheses to support the discovery of improved therapies. (~ https://filizolalab.org) \n 
URL:/pharm/event/dr-marta-filizola/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/04/marta-filizola-250.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
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END:VCALENDAR