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X-WR-CALDESC:Events for Pharmacology
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DTSTART:20250309T070000
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250304T160000
DTEND;TZID=America/New_York:20250304T170000
DTSTAMP:20250428T095824
CREATED:20250114T202148Z
LAST-MODIFIED:20250114T203325Z
UID:10000986-1741104000-1741107600@www.med.unc.edu
SUMMARY:Dr. Kate White of the University of Southern California presents
DESCRIPTION:Kate White\, PhD\nGabilan Assistant Professor of Chemistry\nDepartment of Chemistry\nUniversity of Southern California \nSeminar Title: “Chemical biology approaches for mapping peptide hormone maturation” \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHost: Rob Nicholas\n \nDr. White studies secretion in pancreatic beta cells and neuron and is a former postdoc of the Nicholas and Roth Labs. \n“Our lab focuses on developing new chemical biology tools to uncover how cells coordinate the secretion of peptide hormones—small chains of amino acids that circulate in the blood and bind to specific cell receptors. Defects in the storage\, maturation (enzymatic cleavage)\, or secretion of these hormones can lead to various mental and metabolic disorders\, including depression\, bipolar disorder\, and diabetes. Using pancreatic β-cells and neurons as model systems\, we investigate how these cells reorganize during peptide hormone production\, trafficking\, and secretion. Despite the critical role of this secretion mechanism\, the cellular signals regulating secretory vesicle maturation are still unclear. To address this knowledge gap\, our lab has four main research directions:  \n\n\nDefine signaling pathways that regulate peptide hormone maturation. \n\n\nInvestigate the biochemical role of inter-organelle communication in regulating secretory systems. \n\n\nExamine the biochemical role of cellular and organelle subtypes in secretory cells. \n\n\nDevelop community-based tools to support the next generation of cellular modeling.” \n\n\n~ https://www.katewhitelab.com/ \nFlyer [pdf]
URL:/pharm/event/dr-kate-white-of-the-university-of-southern-california-presents/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/01/Kate_White_USC-250.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250311T160000
DTEND;TZID=America/New_York:20250311T170000
DTSTAMP:20250428T095824
CREATED:20250217T201108Z
LAST-MODIFIED:20250217T201108Z
UID:10000995-1741708800-1741712400@www.med.unc.edu
SUMMARY:Dr. Gerald Shadel of the Salk Institute for Biological Sciences presents
DESCRIPTION:Gerald Shadel\, PhD\nProfessor\nMolecular and Cell Biology Laboratory\nAudrey Geisel Chair in Biomedical Science\nDirector\, San Diego-Nathan Shock Center of Excellence in the Basic Biology of Aging\nSalk Institute for Biological Studies \nSeminar title: “Mitochondrial Signaling in Aging\, Disease and Immunity” \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHost: Lee Graves \n“Gerald Shadel studies the basic biology of mitochondria and mtDNA\, and\, in doing so\, has identified novel ways that mitochondria contribute to disease\, aging and the immunesystem. He is also interested in understanding how mitochondria are involved in cellular signaling processes. He seeks to identify what the signals are\, what pathways they trigger and how they play a part in aging\, cancer and metabolic and degenerative diseases. His group takes a multidisciplinary view\, exploring mitochondrial function—and dysfunction—via cultured cells\, model organisms and other genetic and biochemical approaches.” \n~ https://www.salk.edu/scientist/gerald-shadel/\nLab website: https://shadel.salk.edu/ \nFlyer [pdf]
URL:/pharm/event/dr-gerald-shadel-of-the-salk-institute-for-biological-sciences-presents/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/01/gerald-shadel-250-2.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250318T160000
DTEND;TZID=America/New_York:20250318T170000
DTSTAMP:20250428T095824
CREATED:20250312T140829Z
LAST-MODIFIED:20250312T141650Z
UID:10001001-1742313600-1742317200@www.med.unc.edu
SUMMARY:POSTPONED - Dr. Kenneth A. Jacobson from the National Institutes of Health presents
DESCRIPTION:Kenneth A. Jacobson\, PhD\nJohn W. Daly Distinguished Scientist\nSenior Investigator\nLaboratory of Bioorganic Chemistry\nNIDDK\, National Institutes of Health \nSeminar Title: “Action of Nucleosides and Nucleotides at Purinergic and Non-Purinergic Drug Targets” \nTHIS SEMINAR HAS BEEN POSTPONED \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHost: Yinglong Miao \nDr. Jacobson is an established medicinal chemist with interests in the structure and pharmacology of receptors and in developing drugs that act as agonists or antagonists of G protein-coupled receptors (GPCRs). His current focus is on receptors for purines\, encompassing both adenosine receptors and P2 receptors\, which are activated by ATP\, UTP and other extracellular nucleotides. His lab has taken an interdisciplinary approach to studying the chemical and biological aspects of these receptors. They have used convergent modeling\, mutagenesis and structure activity approaches to gather information about the three-dimensional structure of the receptors and its relationship to binding and activation functions. \nhttps://www.niddk.nih.gov/about-niddk/staff-directory/biography/jacobson-kenneth \nFlyer [pdf]
URL:/pharm/event/dr-kenneth-a-jacobson-from-the-national-institutes-of-health-presents/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2024/12/Jacobson-Kenneth_250x250.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250321T110000
DTEND;TZID=America/New_York:20250321T120000
DTSTAMP:20250428T095824
CREATED:20250319T143726Z
LAST-MODIFIED:20250319T143726Z
UID:10001003-1742554800-1742558400@www.med.unc.edu
SUMMARY:Student Research Seminars with Kyle Pellegrino\, Lizzy Obarow and Grace Stroman
DESCRIPTION:Kyle Pellegrino\, Cohen Lab\nLizzy Obarow\, Dohlman Lab\nGrace Stroman\, Pruitt Lab \nHosted by Kalynn Van Voorhies\, Kash Lab \nLocation: 4007 GMB \nPizza at 12:00 PM\, following seminar for attendees \nFlyer [pdf]
URL:/pharm/event/student-research-seminars-with-kyle-pellegrino-lizzy-obarow-and-grace-stroman/
LOCATION:4007 Genetic Medicine Building\, 120 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Student Research Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/02/2025_03_21_Pellegrino_Obarow_Stroman.jpg
ORGANIZER;CN="April Villaneuva":MAILTO:april_villanueva@med.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250325T160000
DTEND;TZID=America/New_York:20250325T170000
DTSTAMP:20250428T095824
CREATED:20250310T204042Z
LAST-MODIFIED:20250310T204133Z
UID:10001000-1742918400-1742922000@www.med.unc.edu
SUMMARY:Dr. Megan Agajanian of Stanford presents
DESCRIPTION:Megan Agajanian\, PhD\nPostdoctoral Scholar\, Roel Nuuse Lab\nDepartment of Developmental Biology\nStanford University \nSeminar title: “The dynamic role of TBX3 in “The dynamic role of TBX3 in cancer and development” \nLocation: 1131 Bioinformatics \nPlease join us and show support for our seminar speakers!\n(For those unable to attend\, a zoom link is available upon request to Mimi Baltz.) \nHost: Mike Emanuele \nMegan is a postdoc in Roul Nouse’s lab\, the person who first identified Wnt signaling in humans. She is a former Pharmacology student in the Emanuele Lab.  She has been funded by HHMI Gilliam and a K00 Award\, and was selected for the NSF-ASCB FRED Program. \nDr. Agajanian is interested in lineage plasticity and the signals that drive diverse cellular responses. Her postdoctoral work focuses on the dynamic role of TBX3 in breast cancer and mammary gland development. TBX3 mutations in the developing embryo result in Ulnar Mammary Syndrome\, which is characterized by incomplete mammary gland development. In contrast\, TBX3 is mutated in breast cancer and is associated with metastasis. Despite these critical roles of TBX3\, the role of patient mutations in breast cancer progression and the role of TBX3 in postnatal mammary gland expansion remain virtually unstudied. Using organoid and mouse models\, we have demonstrated TBX3 supports organoid growth and in vivo is required for mammary gland expansion during puberty. Interestingly\, previous work identified TBX3 as a lineage specific component of the Wnt transcriptional complex in colorectal cancer\, but it’s role in Wnt signaling in the mammary gland remains unknown. With her background in Wnt signaling interrogation\, in the future\, she aims to pursue her interest in lineage and context dependent regulators of this critical signaling cascade using a wide array of techniques\, including organoid models\, molecular biology\, proteomic\, and in vivo approaches. \n“My project focuses on TBX3 (T-Box Transcription Factor 3)\, one of the top ten mutated genes in breast cancer. TBX3 upregulation and loss of function mutations are identified in patients\, raising the question: is TBX3 a proto-oncogene or tumor suppressor? My work in the Nusse lab will define the role of TBX3 in breast cancer progression and identify TBX3 targets that can be utilized as therapeutic targets in TBX3-associated breast cancer.” ~ https://nusselab.stanford.edu/people/megan-agajanian/ \nFlyer [pdf]
URL:/pharm/event/dr-megan-agajanian-of-stanford-presents/
LOCATION:1131 Bioinformatics\, 130 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Pharmacology Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/01/megan-agajanian-250.jpg
ORGANIZER;CN="Mimi Baltz":MAILTO:my.le@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20250328T110000
DTEND;TZID=America/New_York:20250328T120000
DTSTAMP:20250428T095824
CREATED:20250327T154510Z
LAST-MODIFIED:20250327T154510Z
UID:10001005-1743159600-1743163200@www.med.unc.edu
SUMMARY:Student Research Seminars with Scott Bang\, Amy Aponte and Ryan Robb
DESCRIPTION:Scott Bang\, Morris Lab\nAmy Aponte\, Emanuele Lab\nRyan Robb\, Bryant Lab \nHosted by Emma Armstrong\, Morris Lab \nLocation: 4007 GMB \nPizza at 12:00 PM\, following seminar for attendees \nFlyer [pdf]
URL:/pharm/event/student-research-seminars-with-scott-bang-amy-aponte-and-ryan-robb/
LOCATION:4007 Genetic Medicine Building\, 120 Mason Farm Rd\, Chapel Hill\, North Carolina\, 27514\, United States
CATEGORIES:Student Research Seminars
ATTACH;FMTTYPE=image/jpeg:/pharm/wp-content/uploads/sites/930/2025/03/2025_03_28_student_seminar_flyer_Bang_Aponte_Robb.jpg
ORGANIZER;CN="April Villaneuva":MAILTO:april_villanueva@med.unc.edu
END:VEVENT
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