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The Linnstaedt lab is interested in understanding mechanisms driving the development of chronic musculoskeletal pain following traumatic stress exposures with the goal of identifying novel therapeutic strategies that reduce the burden of chronic pain suffering across the globe. To accomplish this goal, we use translational research methods including the analysis of biological data from longitudinal observational human cohort studies and behavioral, molecular, and cell culture models of the human pain condition. We are particularly interested in the role that the physiological stress system plays in chronic pain development and are also interested in understanding why women are far more vulnerable to chronic pain than men. Overall, my lab鈥檚 goal is to develop at least one novel, non-addictive, therapeutic strategy that is effective at reducing chronic pain in the millions of trauma survivors in need each year.
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CLINICAL/RESEARCH INTERESTS:
Behavior, Computational Biology, Drug Discovery, Epigenetics and Chromatin Biology, Genetics, Genomics, Mental illness, Molecular Biology, Sleep, Systems Biology, Translational Medicine, Veteran鈥檚 Health, Women's Health |