{"id":4379,"date":"2018-07-09T11:03:08","date_gmt":"2018-07-09T15:03:08","guid":{"rendered":"https:\/\/www.med.unc.edu\/neuroscience\/?post_type=directory&#038;p=4379"},"modified":"2019-03-25T14:11:55","modified_gmt":"2019-03-25T18:11:55","slug":"mohanish-deshmukh-phd","status":"publish","type":"directory","link":"https:\/\/www.med.unc.edu\/neuroscience\/directory\/mohanish-deshmukh-phd\/","title":{"rendered":"Mohanish Deshmukh, PhD"},"content":{"rendered":"<h2>Research Description<\/h2>\n<p>We study how neurons control their survival and death. \u00a0Cell death by apoptosis occurs extensively during brain development and is seen in many pathological conditions such as after stroke and neurodegenerative diseases.\u00a0 In contrast, the inability of cells to undergo apoptosis is a fundamental hallmark of cancers.\u00a0 Therefore, understanding the mechanism by which survival and death is regulated is clinically important and has significant translational potential.<\/p>\n<p>We study these mechanisms with molecular and cell biological approaches in primary neurons and human embryonic stem cells in culture, as well as in mouse models of neurodegeneration and brain tumor.<\/p>\n<p><a class=\"external-link\" title=\"\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/myncbi\/browse\/collection\/40869071\/?sort=date&amp;direction=descending\" target=\"_self\">Publications<\/a><\/p>\n<hr \/>\n<h2>Affiliations<\/h2>\n<ul>\n<li><a class=\"external-link\" href=\"http:\/\/www.med.unc.edu\/cellbiophysio\/faculty\/deshmukh\">Cell Biology and Physiology<\/a><\/li>\n<li><a class=\"external-link\" href=\"http:\/\/unclineberger.org\/members\/mohanish-deshmukh\">黑料网 Lineberger Comprehensive Cancer Center, N.C. Cancer Hospital<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Research Description We study how neurons control their survival and death. \u00a0Cell death by apoptosis occurs extensively during brain development and is seen in many pathological conditions such as after stroke and neurodegenerative diseases.\u00a0 In contrast, the inability of cells to undergo apoptosis is a fundamental hallmark of cancers.\u00a0 Therefore, understanding the mechanism by which &hellip; <a href=\"https:\/\/www.med.unc.edu\/neuroscience\/directory\/mohanish-deshmukh-phd\/\" aria-label=\"Read more about Mohanish Deshmukh, PhD\">Read more<\/a><\/p>\n","protected":false},"featured_media":3130,"template":"","meta":{"_acf_changed":false,"_links_to":"","_links_to_target":""},"class_list":["post-4379","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Mohanish Deshmukh, PhD | 黑料网 Neuroscience Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/neuroscience\/directory\/mohanish-deshmukh-phd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mohanish Deshmukh, PhD | 黑料网 Neuroscience Center\" \/>\n<meta property=\"og:description\" content=\"Research Description We study how neurons control their survival and death. \u00a0Cell death by apoptosis occurs extensively during brain development and is seen in many pathological conditions such as after stroke and neurodegenerative diseases.\u00a0 In contrast, the inability of cells to undergo apoptosis is a fundamental hallmark of cancers.\u00a0 Therefore, understanding the mechanism by which &hellip; 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