黑料网 Neuroscience Center /neuroscience/ Thu, 27 Mar 2025 18:09:45 +0000 en-US hourly 1 Advancing Brain Research: The Frohlich Lab’s Work in Neurostimulation and Mental Health /neuroscience/advancing-brain-research-the-frohlich-labs-work-in-neurostimulation-and-mental-health/ Thu, 27 Mar 2025 18:09:45 +0000 /neuroscience/?p=7349 The Frohlich Lab, led by Flavio Frohlich, PhD, professor of psychiatry and of the Carolina Center for Neurostimulation, and specializes in groundbreaking research and developing innovative approaches to combating mental health issues. Watch a video about this research here.

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The Frohlich Lab, led by Flavio Frohlich, PhD, professor of psychiatry and of the Carolina Center for Neurostimulation, and specializes in groundbreaking research and developing innovative approaches to combating mental health issues.

Watch a video about this research .

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黑料网 Neuroscience Faculty Receive BBRF Distinguished Investigator Grants /neuroscience/unc-neuroscience-faculty-receive-bbrf-distinguished-investigator-grants/ Wed, 19 Mar 2025 16:08:38 +0000 /neuroscience/?p=7339 In 2025, the聽Brain & Behavior Research Foundation聽awarded Distinguished Investigator Grants valued at $1 million to 10 senior-level scientists who are conducting groundbreaking research in neurobiological and behavioral science. Recipients of the $100,000, one-year grants are exploring critical areas of mental health, including opioid use disorder, depression in pregnant women, schizophrenia, bipolar disorder, and the effects … Read more

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In 2025, the聽聽awarded Distinguished Investigator Grants valued at $1 million to 10 senior-level scientists who are conducting groundbreaking research in neurobiological and behavioral science. Recipients of the $100,000, one-year grants are exploring critical areas of mental health, including opioid use disorder, depression in pregnant women, schizophrenia, bipolar disorder, and the effects of psychedelics on perception and consciousness.

Recipients of the Distinguished Investigator Grants are full professors at research institutions in the United States and abroad. They were selected by a committee of the BBRF Scientific Council, which is comprised of 192 experts across disciplines in brain and behavior research who review grant applications and recommend the most promising ideas to fund.

The Recipients of the 2025 Distinguished Investigator Grants are as follows:

E. S. Anton, Ph.D., University of North Carolina at Chapel Hill, will investigate signaling molecules and processes (the 鈥渟ignalome鈥) engaged when the primary cilium of neurons is activated, including how it might be harnessed in the service of neural circuit modulation and correction. The hope is to establish how deregulated primary cilia signaling interferes with neural circuit dynamics and contributes to circuit malfunction.

 

 

Flavio Frohlich, Ph.D., University of North Carolina at Chapel Hill, will develop and test a novel non-invasive neurostimulation approach (aperiodic tACS) designed to rapidly reduce depression symptoms in women who are pregnant. tACS, or transcranial alternating current stimulation, has been shown to be safe and effective in major depressive disorder in several pilot trials.

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FDA Grants Breakthrough Device Designation for Non-Invasive Brain Stimulation Device to Treat Major Depressive Disorder /neuroscience/fda-grants-breakthrough-device-designation-for-non-invasive-brain-stimulation-device-to-treat-major-depressive-disorder/ Thu, 13 Mar 2025 18:55:16 +0000 /neuroscience/?p=7334 With a designation from the FDA, a device created and patented by Flavio Frohlich, PhD, professor of psychiatry at the 黑料网 and member of the 黑料网 Neuroscience Center, is one step closer to being available for patients. Original full article can be found here.

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With a designation from the FDA, a device created and patented by Flavio Frohlich, PhD, professor of psychiatry at the 黑料网 and member of the 黑料网 Neuroscience Center, is one step closer to being available for patients.

Original full article can be found .

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Eight Psychiatric Disorders Share the Same Genetic Causes, Study Says /neuroscience/eight-psychiatric-disorders-share-the-same-genetic-causes-study-says/ Thu, 23 Jan 2025 14:52:13 +0000 /neuroscience/?p=7320 A new genetic study, led by聽Hyejung Won, PhD, associate professor in the聽Department of Genetics聽and the聽黑料网 Neuroscience Center, and聽Patrick Sullivan, MD, FRANZCP, the Yeargen Distinguished Professor of Psychiatry and Genetics, has successfully delineated the functional consequences of genetic variants into two groups. Their findings, which聽were published听颈苍听Cell, suggest that pleiotropic variants may be optimal targets for treatment, … Read more

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A new genetic study, led by聽Hyejung Won, PhD, associate professor in the聽Department of Genetics聽and the聽黑料网 Neuroscience Center, and聽Patrick Sullivan, MD, FRANZCP, the Yeargen Distinguished Professor of Psychiatry and Genetics, has successfully delineated the functional consequences of genetic variants into two groups. Their findings, which聽听颈苍听Cell, suggest that pleiotropic variants may be optimal targets for treatment, due to their extended roles in development and sensitivity to change.

Original full article can be found .

 

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Structure-guided design of a peripherally restricted chemogenetic system /neuroscience/structure-guided-design-of-a-peripherally-restricted-chemogenetic-system/ Thu, 02 Jan 2025 15:24:42 +0000 /neuroscience/?p=7315 Kang et聽al. present HCAD, a peripherally restricted DREADD based on HCA2, with a chemical actuator that avoids crossing the blood-brain barrier and selectively reduces pain in mice. This system will enable the study of peripheral physiology without affecting the central nervous system. Publication found here.

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Kang et聽al. present HCAD, a peripherally restricted DREADD based on HCA2, with a chemical actuator that avoids crossing the blood-brain barrier and selectively reduces pain in mice. This system will enable the study of peripheral physiology without affecting the central nervous system.

Publication found .

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Ginty Named 23rd Perl-黑料网 Neuroscience Prize Recipient /neuroscience/ginty-named-23rd-perl-unc-neuroscience-prize-recipient/ Sun, 22 Dec 2024 23:21:36 +0000 /neuroscience/?p=7302 Harvard Neuroscientist David D. Ginty, PhD, will receive the Perl-黑料网 Neuroscience Prize for his pivotal discoveries on the sensation of touch and how our body communicates with the brain. Original full article can be found here.

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Harvard Neuroscientist David D. Ginty, PhD, will receive the Perl-黑料网 Neuroscience Prize for his pivotal discoveries on the sensation of touch and how our body communicates with the brain.

Original full article can be found .

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Sarah Cohen and her collaborators received a 2024 Allen Distinguished Investigator Award /neuroscience/sarah-cohen-and-her-collaborators-received-a-2024-allen-distinguished-investigator-award/ Fri, 06 Dec 2024 14:47:53 +0000 /neuroscience/?p=7299 Sarah Cohen and her collaborators received a 2024 Allen Distinguished Investigator Award to develop a game-changing microscopy tool for visualizing multiple organelles in live cells. Original full article can be found here.

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Sarah Cohen and her collaborators received a 2024 Allen Distinguished Investigator Award to develop a game-changing microscopy tool for visualizing multiple organelles in live cells.

Original full article can be found here.

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Psychiatry Researchers Investigate Why Some Adolescents Lose Motivation and Pleasure /neuroscience/psychiatry-researchers-investigate-why-some-adolescents-lose-motivation-and-pleasure/ Thu, 14 Nov 2024 20:17:19 +0000 /neuroscience/?p=7292 Aysenil Belger, PhD, professor of psychiatry, and Danielle Roubinov, PhD, director of the Child and Adolescent Anxiety and Mood Disorders Program, will lead an innovative study of the predictors of anhedonia 鈥 a common symptom of mental health conditions 鈥 in young people. Original full article can be found here.

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Aysenil Belger, PhD, professor of psychiatry, and Danielle Roubinov, PhD, director of the Child and Adolescent Anxiety and Mood Disorders Program, will lead an innovative study of the predictors of anhedonia 鈥 a common symptom of mental health conditions 鈥 in young people.

Original full article can be found here.

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黑料网 Startup Creates Eye-Tracking Technology to Potentially Help Regulate Psychiatric Symptoms /neuroscience/unc-startup-creates-eye-tracking-technology-to-potentially-help-regulate-psychiatric-symptoms/ Thu, 14 Nov 2024 20:09:17 +0000 /neuroscience/?p=7284 In a 黑料网-Chapel Hill neuroscience lab, researchers recently monitored a mouse wearing a miniature, helmet-like device that streamed real-time data to a nearby computer. As data points on heart rate, pupil size and breathing patterns scrolled across the screen, capturing the intricate interplay between animal physiology and behavior, they realized that their device was more … Read more

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In a 黑料网-Chapel Hill neuroscience lab, researchers recently monitored a mouse wearing a miniature, helmet-like device that streamed real-time data to a nearby computer. As data points on heart rate, pupil size and breathing patterns scrolled across the screen, capturing the intricate interplay between animal physiology and behavior, they realized that their device was more than just another research tool but a groundbreaking advancement in behavioral science鈥攐ne where internal physiological states can finally be measured with precision, potentially revolutionizing several fields from preclinical and clinical neuroscience research to virtual reality.

Full original article can be found .

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Let Sleeping Babies Lie: Scientists Highlight Negative Impacts of Sleep Disruption on Early Brain Development /neuroscience/let-sleeping-babies-lie-scientists-highlight-negative-impacts-of-sleep-disruption-on-early-brain-development/ Thu, 24 Oct 2024 18:09:52 +0000 /neuroscience/?p=7281 The lab of Graham Diering, PhD, assistant professor of cell biology and physiology at the 黑料网, shows how sleep loss during early life impacts key aspects of brain development and how it can increase one鈥檚 risk for developing autism spectrum disorder. Original full article can be found here.

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The lab of Graham Diering, PhD, assistant professor of cell biology and physiology at the 黑料网, shows how sleep loss during early life impacts key aspects of brain development and how it can increase one鈥檚 risk for developing autism spectrum disorder.

Original full article can be found .

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