Research Description
We seek to understand the pathophysiology underlying monogenic neurodevelopmental disorders, and we use this information to develop therapeutics to treat these disorders.聽 To accomplish these goals, we employ a variety of techniques: electrophysiology, biochemistry, molecular biology, optogenetics, behavioral phenotyping, gene therapy, and small-molecule drug screening.聽 We are particularly focused on developing transformative treatments for Dup15q syndrome, Pitt-Hopkins syndrome, and Angelman syndrome.
