Congratulations to the Lab of Brian C. Jensen, M.D., Associate Professor of Medicine and Pharmacology, in collaboration with , Assistant Professor, Department of Physiology, and , Assistant Professor, Department of Physiology, both with Eastern Carolina University (ECU), for the first renewal of R01 grant, entitled 鈥淢etabolic mechanisms of cardioprotection through alpha-1A adrenergic receptor activation鈥�, from the NIH.
This funding mechanism provides $2.5 million over 5 years and is designed to support ongoing investigation of the adaptive effects of alpha-1A adrenergic receptors on mitochondrial function in the heart. The proposed work will also seek to define whether antagonists of alpha-1A adrenergic receptors, commonly used to treat prostate disorders, adversely affect cardiometabolic risk.