John Buse, MD, PhD, Verne S. Caviness Distinguished Professor of Medicine in the Division of Endocrinology & Metabolism, led a study finding 24% of individuals with difficult-to-control type 2 diabetes also present with hypercortisolism (Cushing鈥檚 syndrome). This study, entitled CATALYST and published in Diabetes Care, was the largest and most rigorous trial ever conducted to assess the prevalence of hypercortisolism in patients with difficult-to-control type 2 diabetes.
鈥淢any patients have uncontrolled type 2 diabetes despite the use of the best available medications,鈥� said Dr. Buse. 鈥淚t is critical for clinicians to consider and address all factors that can contribute to inadequate glucose control. CATALYST鈥檚 results show that, for many patients, hypercortisolism is one of those factors.鈥�