Division of Endocrinology and Metabolism /medicine/endocrinology-metabolism/ Department of Medicine Tue, 08 Apr 2025 17:07:15 +0000 en-US hourly 1 Oral Semaglutide and Cardiovascular Outcomes in High-Risk Type 2 Diabetes https://www.nejm.org/doi/full/10.1056/NEJMoa2501006 Tue, 08 Apr 2025 16:03:45 +0000 /medicine/endocrinology-metabolism/?p=3877 John Buse, MD, PhD, was the senior author of this study published in the New England Journal of Medicine. The study found people with type 2 diabetes and heart disease, kidney disease, or both, who took oral semaglutide had a significantly lower risk of major heart-related problems compared to those taking a placebo, and there …

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]]> Once-Weekly Semaglutide in Adults With Alcohol Use Disorder https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2829811 Mon, 07 Apr 2025 16:33:11 +0000 /medicine/endocrinology-metabolism/?p=3885 Klara Klein, MD, PhD, was senior author of this clinical trial showing low-dose semaglutide reduced the amount of alcohol consumed during a posttreatment laboratory self-administration procedure.

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]]> Inhaled Insulin in Type 1 Diabetes https://diabetesjournals.org/care/article/48/3/353/157574/A-Randomized-Trial-Comparing-Inhaled-Insulin-Plus Sun, 06 Apr 2025 16:38:57 +0000 /medicine/endocrinology-metabolism/?p=3887 EnDO CRU investigators helped evaluate a regimen of inhaled Technosphere insulin (TI) plus insulin degludec in adults with type 1 diabetes.

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]]> Deficits in brain glucose transport among younger adults with obesity https://onlinelibrary.wiley.com/doi/10.1002/oby.24034 Sat, 05 Apr 2025 16:53:05 +0000 /medicine/endocrinology-metabolism/?p=3894 Janice Hwang, MD, MHS, and Brooke Matson, MD, PhD, investigated the effect of obesity on brain energy utilization, including brain glucose transport and metabolism.

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]]> Executive function and pump use in teens with type 1 diabetes https://www.liebertpub.com/doi/10.1089/dia.2024.0574?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed Fri, 04 Apr 2025 17:00:06 +0000 /medicine/endocrinology-metabolism/?p=3898 Rebecca Vitale, MD, MPH, was first author for this study evaluating the risks and benefits of insulin pumps in teens with executive function challenges.  

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]]> Glucokinase activators in type 1 diabetes: a Phase 1b/2 Adaptive Study https://diabetesjournals.org/care/article/44/4/960/138590/The-SimpliciT1-Study-A-Randomized-Double-Blind Thu, 03 Apr 2025 17:03:16 +0000 /medicine/endocrinology-metabolism/?p=3900 Klara Klein, MD, PhD, was first author for a randomized controlled trial determining whether TTP399, a novel hepatoselective glucokinase activator, improved glycemic control in people with type 1 diabetes without increasing hypoglycemia or ketosis.

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