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Scott H. Randell, PhD

Professor

Specialty Areas

Airway Epithelial Stem Cells, Airway Innate Immunity and Response to Injury, mRNA regulation

Research Focus

Identification of airway epithelial stem cells. Dr. Randell’s goals are to identify and isolate airway epithelial stem cells and to understand molecular mechanisms regulating airway epithelial cell proliferation and fate decisions.Research in Dr. Randell’s laboratory is currently focused on five areas where a greater knowledge of basic cell biology can be applied towards overcoming clinical lung disease problems:

  • Micro RNA Regulation of Human Airway Epithelial Phenotype- ARRA Award. The Randell Laboratory comprehensively determines the miRNA repertoire of human airway epithelial cells will tests the ability of miRNAs to alter cell structure and function. These studies will create a valuable database and will suggest novel treatments for lung disease.
  • Innate immunity in the airway. Dr Randell aims to better understand molecular mechanisms regulating airway epithelial adaptation to injury and chronic infection and to understand the relationship of adaptation to the pathogenesis of airway disease.
  • Post-lung transplant ischemia reperfusion injury and bronchiolitis obliterans syndrome. The Randell Laboratory is also examining basic mechanisms of lung injury relevant to transplantation and bronchiolitis obliterans syndrome, the leading cause of lung allograft failure.
  • Dr. Scott Randell also directs the ºÚÁÏÍø Marsico Lung Institute (MLI) Tissue Procurement and Cell Culture Core, which provides primary and passaged human airway and alveolar epithelial cells, lung microvascular endothelial cells, media and expertise to ºÚÁÏÍø MLI investigators and collaborators. Our facility has become a nationally and internationally recognized resource whose services are sought for collaboration, contract research, and training by academics, non-profit organizations, biotech and the pharmaceutical industry.
Confocal microscopy image of cultured human airway epithelial cells expressing green and red fluorescent protein
Figure 1. X-Y plane confocal microscopy of cultured human airway epithelial cells expressing green and red fluorescent protein.
Microscopy images of human bronchial epithelial cells in culture
Figure 2. Human bronchial epithelial cells in culture, fixed with perflurocarbon OsO4 and prepared for high resolution light microscopy.
Images of a frozen section of a human cystic fibrosis airway
Figure 3. Frozen section of a human cystic fibrosis airway excised during lung transplantation, stained for mucus. Note the adhesion between the mucus in the lumen and the airway wall.

Staff

Close-up shot of Teresa Mascenik working in a laboratory

Teresa Mascenik
Research Specialist

Close-up shot of Tuong Nguyen in a laboratory

Tuong Nguyen
Research Technician

Headshot of Rhianna Lee

Rhianna Lee
Research Collaborator

Selected Bibliography

  1. Saferali A, Wienecke AN, Xu Z, Liu T, Sheynkman GM, Hersh CP, Cho MH, Silverman EK, Zhou X, Wilson CL, Schnapp LM, Randell SH, Ramos SBV, Laederach A, Vollmers C, Castaldi PJ. . Eur Respir J. 2025 Apr 3;65(4):2401407. doi: 10.1183/13993003.01407-2024. PMID: 39978861.PMCID: PMC11968218.
  2. Ghosh A, Rogers KL Jr, Gallant SC, Brocke SA, Speen AM, Kim YH, Gilmour MI, Randell SH, Jaspers I. . Toxicol Sci. 2025 Mar 1;204(1):2-8. doi: 10.1093/toxsci/kfae161. PMID: 39673801. PMCID: PMC11879058.
  3. Mwase C, Schworer SA, Gilmore RC, Khan F, Dy ABC, Haber AL, Boucher RC Jr, Randell SH, Mackman N, Park JA. . Am J Respir Cell Mol Biol. 2025 Jan 7. doi: 10.1165/rcmb.2024-0130OC. Epub ahead of print. PMID: 39773168.
  4. Lehmann M, Krishnan R, Sucre J, Kulkarni HS, Pineda RH, Anderson C, Banovich NE, Behrsing HP, Dean CH, Haak A, Gosens R, Kaminski N, Zagorska A, Koziol-White C, Metcalf JP, Kim YH, Loebel C, Neptune E, Noel A, Raghu G, Sewald K, Sharma A, Suki B, Sperling A, Tatler A, Turner S, Rosas IO, van Ry P, Wille T, Randell SH, Pryhuber G, Rojas M, Bourke J, Königshoff M. . Am J Respir Cell Mol Biol. 2024 Nov 5. doi: 10.1165/rcmb.2024-0479ST. Epub ahead of print. PMID: 39499861. PMCID: PMC11707673.
  5. Pickles RJ, Chen G, Randell SH. . J Clin Invest. 2024 Nov 1;134(21):e185689. doi: 10.1172/JCI185689. PMID: 39484717; PMCID: PMC11527439.
  6. Ghosh A, Rogers KL Jr, Gallant SC, Kim YH, Rager JE, Gilmour MI, Randell SH, Jaspers I. . Part Fibre Toxicol. 2024 Oct 8;21(1):41. doi: 10.1186/s12989-024-00604-7. PMID: 39380034; PMCID: PMC11460082.
  7. Cheng C, Katoch P, Zhong YP, Higgins CT, Moredock M, Chang MEK, Flory MR, Randell SH, Streeter PR. . Int J Mol Sci. 2024 Sep 12;25(18):9863. doi: 10.3390/ijms25189863. PMID: 39337350; PMCID: PMC11432080.
  8. Liang K, Barnett KC, Hsu M, Chou WC, Bais SS, Riebe K, Xie Y, Nguyen TT, Oguin TH 3rd, Vannella KM, Hewitt SM, Chertow DS, Blasi M, Sempowski GD, Karlsson A, Koller BH, Lenschow DJ, Randell SH, Ting JP. . Sci Immunol. 2024 Jul 12;9(97):eadn0178. doi: 10.1126/sciimmunol.adn0178. PMID: 38996010. PMCID: PMC11970318.
  9. Easter QT, Fernandes Matuck B, Beldorati Stark G, Worth CL, Predeus AV, Fremin B, Huynh K, Ranganathan V, Ren Z, Pereira D, Rupp BT, Weaver T, Miller K, Perez P, Hasuike A, Chen Z, Bush M, Qu X, Lee J, Randell SH, Wallet SM, Sequeira I, Koo H, Tyc KM, Liu J, Ko KI, Teichmann SA, Byrd KM. . Nat Commun. 2024 Jun 14;15(1):5016. doi: 10.1038/s41467-024-49037-y. PMID: 38876998; PMCID: PMC11178863.
  10. Chen Q, Hirai H, Chan M, Zhang J, Cho M, Randell SH, Kadur Lakshminarasimha Murthy P, Rehman J, Liu Y. . Stem Cell Reports. 2024 Jun 11;19(6):890-905. doi: 10.1016/j.stemcr.2024.04.009. PMID: 38759645. PMCID: PMC11390684.
  11. Ghosh A, Payton A, Gallant SC, Rogers KL Jr, Mascenik T, Hickman E, Love CA, Schichlein KD, Smyth TR, Kim YH, Rager JE, Gilmour MI, Randell SH, Jaspers I. . Chem Res Toxicol. 2024 May 20;37(5):791-803. doi: 10.1021/acs.chemrestox.4c00064. PMID: 38652897. PMCID: PMC11251002 .
  12. Meganck RM, Edwards CE, Mallory ML, Lee RE, Dang H, Bailey AB, Wykoff JA, Gallant SC, Zhu DR, Yount BL, Kato T, Shaffer KM, Nakano S, Cawley AM, Sontake V, Wang JR, Hagan RS, Miller MB, Tata PR, Randell SH, Tse LV, Ehre C, Okuda K, Boucher RC, Baric RS. . Cell Rep. 2024 Apr 23;43(4):114076. doi: 10.1016/j.celrep.2024.114076. PMID: 38607917. PMCID: PMC11165423.
  13. Lee RE, Mascenik TM, Major SC, Galiger JR, Bulik-Sullivan E, Siesser PF, Lewis CA, Bear JE, Le Suer JA, Hawkins FJ, Pickles RJ, Randell SH. . Am J Physiol Lung Cell Mol Physiol. 2024 Mar 1;326(3):L226-L238. doi: 10.1152/ajplung.00421.2022. PMID: 38150545. PMCID: PMC11280688.
  14. Asakura T, Okuda K, Chen G, Dang H, Kato T, Mikami Y, Schworer SA, Gilmore RC, Radicioni G, Hawkins P, Barbosa Cardenas SM, Saito M, Cawley AM, De la Cruz G, Chua M, Alexis NE, Masugi Y, Noone PG, Ribeiro CMP, Kesimer M, Olivier KN, Hasegawa N, Randell SH, O’Neal WK, Boucher RC. . Am J Respir Crit Care Med. 2024 Feb 15;209(4):374-389. doi: 10.1164/rccm.202306-1093OC. PMID: 38016030. PMCID: PMC10878387.
  15. Hou YJ, Chiba S, Leist SR, Meganck RM, Martinez DR, Schäfer A, Catanzaro NJ, Sontake V, West A, Edwards CE, Yount B, Lee RE, Gallant SC, Zost SJ, Powers J, Adams L, Kong EF, Mattocks M, Tata A, Randell SH, Tata PR, Halfmann P, Crowe JE Jr, Kawaoka Y, Baric RS. . Nat Microbiol. 2023 Oct;8(10):1820-1833. doi: 10.1038/s41564-023-01476-x. PMID: 37749254; PMCID: PMC10522490.
  16. Tse LV, Hou YJ, McFadden E, Lee RE, Scobey TD, Leist SR, Martinez DR, Meganck RM, Schäfer A, Yount BL, Mascenik T, Powers JM, Randell SH, Zhang Y, Wang L, Mascola J, McLellan JS, Baric RS. . Sci Transl Med. 2023 Sep 27;15(715):eadg5567. doi: 10.1126/scitranslmed.adg5567. PMID: 37756379. PMCID: PMC11292784 .
  17. Ma L, Thapa BR, Le Suer JA, Tilston-Lünel A, Herriges MJ, Berical A, Beermann ML, Wang F, Bawa PS, Kohn A, Ysasi AB, Kiyokawa H, Matte TM, Randell SH, Varelas X, Hawkins FJ, Kotton DN. . Cell Stem Cell. 2023 Sep 7;30(9):1199-1216.e7. doi: 10.1016/j.stem.2023.07.014. PMID: 37625411. PMCID: PMC10528754.
  18. Lee RE, Reidel B, Nelson MR, Macdonald JK, Kesimer M, Randell SH.Ìý. Adv Drug Deliv Rev. 2023 Jul;198:114866. doi: 10.1016/j.addr.2023.114866. PMID: 37196698.ÌýPMCID: PMC10336980.
  19. Mikami Y, Grubb BR, Rogers TD, Dang H, Asakura T, Kota P, Gilmore RC, Okuda K, Morton LC, Sun L, Chen G, Wykoff JA, Ehre C, Vilar J, van Heusden C, Livraghi-Butrico A, Gentzsch M, Button B, Stutts MJ, Randell SH, O’Neal WK, Boucher RC. . Sci Transl Med. 2023 Jun 7;15(699):eabo7728. doi: 10.1126/scitranslmed.abo7728. PMID: 37285404. PMCID: PMC10664029.
  20. Tyrrell J, Ghosh A, Manzo ND, Randell SH, Tarran R. . J Appl Toxicol. 2023 Jun;43(6):862-873. doi: 10.1002/jat.4430. PMID: 36594405.
  21. Rustam S, Hu Y, Mahjour SB, Rendeiro AF, Ravichandran H, Urso A, D’Ovidio F, Martinez FJ, Altorki NK, Richmond B, Polosukhin V, Kropski JA, Blackwell TS, Randell SH, Elemento O, Shaykhiev R. . Am J Respir Crit Care Med. 2023 May 1;207(9):1171-1182. doi: 10.1164/rccm.202207-1384OC. PMID: 36796082. PMCID: PMC10161760.
  22. Barnett KC, Xie Y, Asakura T, Song D, Liang K, Taft-Benz SA, Guo H, Yang S, Okuda K, Gilmore RC, Loome JF, Oguin III TH, Sempowski GD, Randell SH, Heise MT, Leo Lei Y†, Boucher RC†, Ting JPY†.Ìý. Cell Host Microbe.Ìý2023 Feb 8;31(2):243-259.e6. doi: 10.1016/j.chom.2022.12.005. PMID: 36563691. PMCID: PMC9731922.Ìý†These authors equally supervised this work.
  23. Kato T, Asakura T, Edwards CE, Dang H, Mikami Y, Okuda K, Chen G, Sun L, Gilmore RC, Hawkins P, De la Cruz G, Cooley MR, Bailey AB, Hewitt SM, Chertow DS, Borczuk AC, Salvatore S, Martinez FJ, Thorne LB, Askin FB, Ehre C, Randell SH, O’Neal WK, Baric RS, Boucher RC; NIH COVID-19 Autopsy Consortium. . Am J Respir Crit Care Med. 2022 Dec 1;206(11):1336-1352. doi: 10.1164/rccm.202111-2606OC. PMID: 35816430. PMCID: PMC9746856.
  24. Kim J, Rustam S, Mosquera JM, Randell SH, Shaykhiev R, Rendeiro AF, Elemento O. . Nat Methods. 2022 Dec;19(12):1653-1661. doi: 10.1038/s41592-022-01657-2. PMID: 36316562.
  25. Lee RE, Lewis CA, He L, Bulik-Sullivan EC, Gallant SC, Mascenik TM, Dang H, Cholon DM, Gentzsch M, Morton LC, Minges JT, Theile JW, Castle NA, Knowles MR, Kimple AJ, Randell SH. . J Clin Invest. 2022 Sep 15;132(18):e154571. doi: 10.1172/JCI154571. PMID: 35900863; PMCID: PMC9479597.
  26. Esther CR Jr, Kimura KS, Mikami Y, Edwards CE, Das SR, Freeman MH, Strickland BA, Brown HM, Wessinger BC, Gupta VC, Von Wahlde K, Sheng Q, Huang LC, Bacon DR, Kimple AJ, Ceppe AS, Kato T, Pickles RJ, Randell SH, Baric RS, Turner JH, Boucher RC. . Int Forum Allergy Rhinol. 2022 Sep;12(9):1137-1147. doi: 10.1002/alr.22975. PMID: 35040594. PMCID: PMC9011886.
  27. Berical A, Lee RE, Lu J, Beermann ML, Le Suer JA, Mithal A, Thomas D, Ranallo N, Peasley M, Stuffer A, Bukis K, Seymour R, Harrington J, Coote K, Valley H, Hurley K, McNally P, Mostoslavsky G, Mahoney J, Randell SH, Hawkins FJ. . Nat Commun. 2022 Jul 29;13(1):4270. doi: 10.1038/s41467-022-31854-8. PMID: 35906215; PMCID: PMC9338271.
  28. Hamad SH, Montgomery SA, Simon JM, Bowman BM, Spainhower KB, Murphy RM, Knudsen ES, Fenton SE, Randell SH, Holt JR, Hayes DN, Witkiewicz AK, Oliver TG, Major MB, Weissman BE. . Oncogene. 2022 Jun;41(25):3423-3432. doi: 10.1038/s41388-022-02348-0. PMID: 35577980.
  29. Kadur Lakshminarasimha Murthy P, Sontake V, Tata A, Kobayashi Y, Macadlo L, Okuda K, Conchola AS, Nakano S, Gregory S, Miller LA, Spence JR, Engelhardt JF, Boucher RC, Rock JR, Randell SH, Tata PR.Ìý. Nature. 2022 Apr;604(7904):111-119. doi: 10.1038/s41586-022-04541-3. PMID: 35355018. PMCID: PMC9169066.
  30. Kato T, Radicioni G, Papanikolas MJ, Stoychev GV, Markovetz MR, Aoki K, Porterfield M, Okuda K, Barbosa Cardenas SM, Gilmore RC, Morrison CB, Ehre C, Burns KA, White KK, Brennan TA, Goodell HP, Thacker H, Loznev HT, Forsberg LJ, Nagase T, Rubinstein M, Randell SH, Tiemeyer M, Hill DB, Kesimer M, O’Neal WK, Ballard ST, Freeman R, Button B, Boucher RC. . Sci Adv. 2022 Apr;8(13):eabm9718. doi: 10.1126/sciadv.abm9718. PMID: 35363522.
  31. Vaidyanathan S, Baik R, Chen L, Bravo DT, Suarez CJ, Abazari SM, Salahudeen AA, Dudek AM, Teran CA, Davis TH, Lee CM, Bao G, Randell SH, Artandi SE, Wine JJ, Kuo CJ, Desai TJ, Nayak JV, Sellers ZM, Porteus MH.Ìý. Mol Ther.Ìý2022 Jan 5;30(1):223-237. doi: 10.1016/j.ymthe.2021.03.023. PMID: 33794364.ÌýPMCID: PMC8753290.
  32. Kabadi AM, Machlin L, Dalal N, Lee RE, McDowell I, Shah NN, Drowley L, Randell SH, Reddy TE. . J Cyst Fibros. 2022 Jan;21(1):164-171. doi: 10.1016/j.jcf.2021.04.008. PMID: 34049825; PMCID: PMC8613331.
  33. Kong X, Bennett WC, Jania CM, Chason KD, German Z, Adouli J, Budney SD, Oby BT, van Heusden C, Lazarowski ER, Jaspers I, Randell SH, Hedgespeth BA, Cruse G, Hua X, Schworer SA, Smith GJ, Kelada SN, Tilley SL. . JCI Insight. 2021 Nov 8;6(21):e140207. doi: 10.1172/jci.insight.140207. PMID: 34546976; PMCID: PMC8663556.
  34. Sims AC, Mitchell HD, Gralinski LE, Kyle JE, Burnum-Johnson KE, Lam M, Fulcher ML, West A, Smith RD, Randell SH, Metz TO, Sheahan TP, Waters KM, Baric RS. . mBio. 2021 Aug 31;12(4):e0157221. doi: 10.1128/mBio.01572-21. PMID: 34372702; PMCID: PMC8406233.
  35. Okuda K, Randell SH, Birket SE. . Am J Respir Cell Mol Biol. 2021 Aug;65(2):123-125. doi: 10.1165/rcmb.2021-0070ED. PMID: 33831321; PMCID: PMC8399579.
  36. Marozkina N, Smith L, Zhao Y, Zein J, Chmiel JF, Kim J, Kiselar J, Davis MD, Cunningham RS, Randell SH, Gaston B. . Sci Rep. 2021 Jul 29;11(1):15498. doi: 10.1038/s41598-021-94782-5. PMID: 34326365; PMCID: PMC8322277.
  37. Okuda K, Randell SH, Birket SE.Ìý. Am J Respir Cell Mol Biol.Ìý2021 Jul 29;11(1):15498. doi: 10.1165/rcmb.2021-0070ED. PMID: 33831321.ÌýPMCID: PMC8399579.
  38. Benway CJ, Liu J, Guo F, Du F, Randell SH, Cho MH, Silverman EK, Zhou X; International COPD Genetics Consortium. . Am J Respir Cell Mol Biol. 2021 Jul;65(1):92-102. doi: 10.1165/rcmb.2020-0475OC. PMID: 33788674. PMCID: PMC8320120.
  39. Dang Y, van Heusden C, Nickerson V, Chung F, Wang Y, Quinney NL, Gentzsch M, Randell SH, Moulton HM, Kole R, Ni A, Juliano RL, Kreda SM. . Nucleic Acids Res. 2021 Jun 21;49(11):6100-6113. doi: 10.1093/nar/gkab488. PMID: 34107015; PMCID: PMC8216463.
  40. Kato T, Mikami Y, Sun L, Rogers TD, Grubb BR, Morrison CB, Ehre C, Sears PR, Ostrowski LE, Randell SH, Boucher RC. . Am J Respir Cell Mol Biol. 2021 Jun;64(6):760-764. doi: 10.1165/rcmb.2021-0033LE. PMID: 33788673. PMCID: PMC8456889.
  41. Okuda K, Dang H, Kobayashi Y, Carraro G, Nakano S, Chen G, Kato T, Asakura T, Gilmore RC, Morton LC, Lee RE, Mascenik T, Yin WN, Barbosa Cardenas SM, O’Neal YK, Minnick CE, Chua M, Quinney NL, Gentzsch M, Anderson CW, Ghio A, Matsui H, Nagase T, Ostrowski LE, Grubb BR, Olsen JC, Randell SH, Stripp BR, Tata PR, O’Neal WK, Boucher RC. . Am J Respir Crit Care Med. 2021 May 15;203(10):1275-1289. doi: 10.1164/rccm.202008-3198OC. PMID: 33321047. PMCID: PMC8456462.
  42. Carraro G, Langerman J, Sabri S, Lorenzana Z, Purkayastha A, Zhang G, Konda B, Aros CJ, Calvert BA, Szymaniak A, Wilson E, Mulligan M, Bhatt P, Lu J, Vijayaraj P, Yao C, Shia DW, Lund AJ, Israely E, Rickabaugh TM, Ernst J, Mense M, Randell SH, Vladar EK, Ryan AL, Plath K, Mahoney JE, Stripp BR, Gomperts BN. . Nat Med. 2021 May;27(5):806-814. doi: 10.1038/s41591-021-01332-7. PMID: 33958799.
  43. He L, Kennedy AS, Houck S, Aleksandrov A, Quinney NL, Cyr-Scully A, Cholon DM, Gentzsch M, Randell SH, Ren HY, Cyr DM.Ìý. Mol Biol Cell. 2021 Apr 1;32(7):538-553. PMID: 33534640. PMCID: PMC8101465.
  44. Hawkins FJ, Suzuki S, Beermann ML, Barillà C, Wang R, Villacorta-Martin C, Berical A, Jean JC, Le Suer J, Matte T, Simone-Roach C, Tang Y, Schlaeger TM, Crane AM, Matthias N, Huang SXL, Randell SH, Wu J, Spence JR, Carraro G, Stripp BR, Rab A, Sorsher EJ, Horani A, Brody SL, Davis BR, Kotton DN. . Cell Stem Cell. 2021 Jan 7;28(1):79-95.e8. doi: 10.1016/j.stem.2020.09.017. PMID: 33098807; PMCID: PMC7796997.
  45. Hou YJ, Chiba S, Halfmann P, Ehre C, Kuroda M, Dinnon KH 3rd, Leist SR, Schäfer A, Nakajima N, Takahashi K, Lee RE, Mascenik TM, Graham R, Edwards CE, Tse LV, Okuda K, Markmann AJ, Bartelt L, de Silva A, Margolis DM, Boucher RC, Randell SH, Suzuki T, Gralinski LE, Kawaoka Y, Baric RS. . Science. 2020 Dec 18;370(6523):1464-1468. doi: 10.1126/science.abe8499. PMID: 33184236. PMCID: PMC7775736.
  46. Katsura H, Sontake V, Tata A, Kobayashi Y, Edwards CE, Heaton BE, Konkimalla A, Asakura T, Mikami Y, Fritch EJ, Lee PJ, Heaton NS, Boucher RC, Randell SH, Baric RS, Tata PR. . Cell Stem Cell. 2020 Dec 3;27(6):890-904.e8. doi: 10.1016/j.stem.2020.10.005. PMID: 33128895; PMCID: PMC7577733.
  47. Carraro G, Mulay A, Yao C, Mizuno T, Konda B, Petrov M, Lafkas D, Arron JR, Hogaboam CM, Chen P, Jiang D, Noble PW, Randell SH, McQualter JL, Stripp BR. . Am J Respir Crit Care Med. 2020 Dec 1;202(11):1540-1550. doi: 10.1164/rccm.201904-0792OC. PMID: 32692579; PMCID: PMC7706153.
  48. Sigmon JS, Blanchard MW, Baric RS, Bell TA, Brennan J, Brockmann GA, Burks AW, Calabrese JM, Caron KM, Cheney RE, Ciavatta D, Conlon F, Darr DB, Faber J, Franklin C, Gershon TR, Gralinski L, Gu B, Gaines CH, Hagan RS, Heimsath EG, Heise MT, Hock P, Ideraabdullah F, Jennette JC, Kafri T, Kashfeen A, Kulis M, Kumar V, Linnertz C, Livraghi-Butrico A, Lloyd KCK, Lutz C, Lynch RM, Magnuson T, Matsushima GK, McMullan R, Miller DR, Mohlke KL, Moy SS, Murphy CEY, Najarian M, O’Brien L, Palmer AA, Philpot BD, Randell SH, Reinholdt L, Ren Y, Rockwood S, Rogala AR, Saraswatula A, Sassetti CM, Schisler JC, Schoenrock SA, Shaw GD, Shorter JR, Smith CM, St Pierre CL, Tarantino LM, Threadgill DW, Valdar W, Vilen BJ, Wardwell K, Whitmire JK, Williams L, Zylka MJ, Ferris MT, McMillan L, Manuel de Villena FP. . Genetics. 2020 Dec;216(4):905-930. doi: 10.1534/genetics.120.303596. PMID: 33067325; PMCID: PMC7768238.
  49. Harrison EB, Porrello A, Bowman BM, Belanger AR, Yacovone G, Azam SH, Windham IA, Ghosh SK, Wang M, McKenzie N, Waugh TA, Van Swearingen AED, Cohen SM, Allen DG, Goodwin TJ, Mascenik T, Bear JE, Cohen S, Randell SH, Massion PP, Major MB, Huang L, Pecot CV. . Cancer Res. 2020 Nov 15;80(22):4972-4985. doi: 10.1158/0008-5472.CAN-20-1162. PMID: 32978168. PMCID: PMC7669576.
  50. Edwards CE, Yount BL, Graham RL, Leist SR, Hou YJ, Dinnon KH 3rd, Sims AC, Swanstrom J, Gully K, Scobey TD, Cooley MR, Currie CG, Randell SH, Baric RS. . Proc Natl Acad Sci U S A. 2020 Oct 27;117(43):26915-26925. doi: 10.1073/pnas.2001046117. PMID: 33046644; PMCID: PMC7604506.
  51. Bowman BM, Montgomery SA, Schrank TP, Simon JM, Ptacek TS, Tamir TY, Mulvaney KM, Weir SJ, Nguyen TT, Murphy RM, Makowski L, Hayes DN, Chen XL, Randell SH, Weissman BE, Major MB. . J Pathol. 2020 Oct;252(2):125-137. doi: 10.1002/path.5504. PMID: 32619021; PMCID: PMC7511428.
  52. Kasam RK, Gajjala PR, Jegga AG, Courtney JA, Randell SH, Kramer EL, Clancy JP, Madala SK. . J Cyst Fibros. 2020 Sep;19(5):815-822. doi: 10.1016/j.jcf.2020.06.011. PMID: 32593509; PMCID: PMC7492481.
  53. King NE, Suzuki S, Barillà C, Hawkins FJ, Randell SH, Reynolds SD, Stripp BR, Davis BR. . Hum Gene Ther. 2020 Sep;31(17-18):956-972. doi: 10.1089/hum.2020.160. PMID: 32741223; PMCID: PMC7495916.
  54. Lee RE, Miller SM, Mascenik TM, Lewis CA, Dang H, Boggs ZH, Tarran R, Randell SH. . Am J Respir Cell Mol Biol. 2020 Sep;63(3):374-385. doi: 10.1165/rcmb.2019-0384OC. PMID: 32437238; PMCID: PMC7462339.
  55. McQueen BE, Kiatthanapaiboon A, Fulcher ML, Lam M, Patton K, Powell E, Kollipara A, Madden V, Suchland RJ, Wyrick P, O’Connell CM, Reidel B, Kesimer M, Randell SH, Darville T, Nagarajan UM. . Infect Immun. 2020 Aug 19;88(9):e00105-20. doi: 10.1128/IAI.00105-20. PMID: 32601108; PMCID: PMC7440757.
  56. Hou YJ, Okuda K, Edwards CE, Martinez DR, Asakura T, Dinnon III KH, Kato T, Lee RE, Yount BL, Mascenik TM, Chen G, Olivier KN, Ghio A, Tse LV, Leist SR, Gralinski LE, Schäfer A, Dang H, Gilmore R, Fulcher L, Livraghi-Butrico A, Nicely NI, Cameron M, Cameron C, Kelvin DJ, de Silva A, Margolis DM, Markmann A, Bartelt L, Zumwalt R, Martinez FJ, Salvatore SP, Borczuk A, Tata PR, Sontake V, Kimple A, Jaspers I, O’Neal WK, Randell SH, Boucher RC, Baric RS. . Cell. 2020 Jul 23;182(2):429-446.e14. doi: 10.1016/j.cell.2020.05.042. PMID: 32526206; PMCID: PMC7250779.
  57. Suzuki S, Crane AM, Anirudhan V, Barillà C, Matthias N, Randell SH, Rab A, Sorscher EJ, Kerschner JL, Yin S, Harris A, Mendel M, Kim K, Zhang L, Conway A, Davis BR. . Mol Ther. 2020 Jul 8;28(7):1684-1695. doi: 10.1016/j.ymthe.2020.04.021. PMID: 32402246. PMCID: PMC7335734.
  58. Menachery VD, Dinnon KH 3rd, Yount BL Jr, McAnarney ET, Gralinski LE, Hale A, Graham RL, Scobey T, Anthony SJ, Wang L, Graham B, Randell SH, Lipkin WI, Baric RS. . J Virol. 2020 Feb 14;94(5). doi: 10.1128/JVI.01774-19. PMID: 31801868. PMCID: PMC7022341.
  59. Kılıç A, Ameli A, Park JA, Kho AT, Tantisira K, Santolini M, Cheng F, Mitchel JA, McGill M, O’Sullivan MJ, De Marzio M, Sharma A, Randell SH, Drazen JM, Fredberg JJ, Weiss ST. . Sci Rep. 2020 Jan 22;10(1):966. doi: 10.1038/s41598-020-57755-8. PMID: 31969610. PMCID: PMC6976696.
  60. Nguyen TT, Soma PS, Mascenik T, Lewis CA, Lee RE, Thorp BD, Zanation AM, Ebert CS Jr, Senior BA, Randell SH, Ehrmann BM, Kimple AJ. . Int Forum Allergy Rhinol. 2019 Dec;9(12):1451-1455. doi: 10.1002/alr.22441. PMID: 31633879. PMCID: PMC6927533.
  61. Smeekens JM, Immormino RM, Balogh PA, Randell SH, Kulis MD, Moran TP.Ìý. Clin Exp Allergy.Ìý 2019 Nov;49(11):1500-1511. doi: 10.1111/cea.13486. PMID: 31444814. PMCID: PMC7171466.
  62. Chen G, Sun L, Kato T, Okuda K, Martino MB, Abzhanova A, Lin JM, Gilmore RC, Batson BD, Volmer AS, Dang H, Deng Y, Randell SH, Button B, Livraghi-Butrico A, Kesimer M, Ribeiro CMP, O’Neal WK, Boucher RC.. J Clin Invest. 2019 Oct 1;129(10):4433-4450. doi: 10.1172/JCI125669. PMID: 31524632. PMCID: PMC6763234.
  63. Marozkina N, Bosch J, Cotton C, Smith L, Seckler J, Zaman K, Rehman S, Periasamy A, Gaston H, Altawallbeh G, Davis M, Jones DR, Schilz R, Randell SH, Gaston B. . Am J Physiol Lung Cell Mol Physiol. 2019 Aug 1;317(2):L247-L258. doi: 10.1152/ajplung.00020.2019. PMID: 31116581. PMCID: PMC6734384.
  64. Parker MM, Hao Y, Guo F, Pham B, Chase R, Platig J, Cho MH, Hersh CP, Thannickal VJ, Crapo J, Washko G, Randell SH, Silverman EK, San José Estépar R, Zhou X, Castaldi PJ. . Elife. 2019 Jul 25;8. doi: 10.7554/eLife.42720. PMID: 31343404. PMCID: PMC6693893.
  65. Chen G, Ribeiro CMP, Sun L, Okuda K, Kato T, Gilmore RC, Martino MB, Dang H, Abzhanova A, Lin JM, Hull-Ryde EA, Volmer AS, Randell SH, Livraghi-Butrico A, Deng Y, Scherer PE, Stripp BR, O’Neal WK, Boucher RC. . Am J Respir Crit Care Med. 2019 Jul 15;200(2):220-234. doi: 10.1164/rccm.201810-1972OC. PMID: 30973754. PMCID: PMC6635783.
  66. Barrios J, Kho AT, Aven L, Mitchel JA, Park JA, Randell SH, Miller LA, Tantisira KG, Ai X. Am J Respir Cell Mol Biol. 2019 Jun;60(6):687-694. doi: 10.1165/rcmb.2018-0179OC. PMID: 30571139. PMCID: PMC6543741.
  67. Okuda K, Chen G, Subramani DB, Wolf M, Gilmore RC, Kato T, Radicioni G, Kesimer M, Chua M, Dang H, Livraghi-Butrico A, Ehre C, Doerschuk CM, Randell SH, Matsui H, Nagase T, O’Neal WK, Boucher RC. Am J Respir Crit Care Med. 2019 Mar 15;199(6):715-727. doi: 10.1164/rccm.201804-0734OC. PMID: 30352166. PMCID: PMC6423099.
  68. Berical A, Lee RE, Randell SH, Hawkins F. . Front Pharmacol. 2019 Feb 8;10:74. doi: 10.3389/fphar.2019.00074. PMID: 30800069. PMCID: PMC6376457.
  69. Khatri A, Kraft BD, Tata PR, Randell SH, Piantadosi CA, Pendergast AM.Ìý Proc Natl Acad Sci U S A.Ìý2019 Jan 29;116(5):1603-1612. doi: 10.1073/pnas.1816030116. PMID: 30655340. PMCID: PMC6358689.
  70. Panganiban RA, Sun M, Dahlin A, Park HR, Kan M, Himes BE, Mitchel JA, Iribarren C, Jorgenson E, Randell SH, Israel E, Tantisira K, Shore S, Park JA, Weiss ST, Wu AC, Lu Q. J Allergy Clin Immunol. 2018 Nov;142(5):1469-1478.e2. doi: 10.1016/j.jaci.2017.11.040. PMID: 29330013.ÌýPMCID: PMC6037620.
  71. Gupta R, Radicioni G, Abdelwahab S, Dang H, Carpenter J, Chua M, Mieczkowski PA, Sheridan J, Randell SH, Kesimer M. Am J Respir Cell Mol Biol. 2019 Feb;60(2):209-220. doi: 10.1165/rcmb.2018-0156OC. PMID: 30230353. PMCID: PMC6376407.
  72. Ghosh A, Coakley RC, Mascenik T, Rowell TR, Davis ES, Rogers K, Webster MJ, Dang H, Herring LE, Sassano MF, Livraghi-Butrico A, Van Buren SK, Graves LM, Herman MA, Randell SH, Alexis NE, Tarran R. Am J Respir Crit Care Med. 2018 Jul 1;198(1):67-76. doi: 10.1164/rccm.201710-2033OC. PMID: 29481290. PMCID: PMC6034122.
  73. Gillen AE, Yang R, Cotton CU, Perez A, Randell SH, Leir SH, Harris A. J Cyst Fibros. 2018 Jul;17(4):444-453. doi: 10.1016/j.jcf.2018.01.009. PMID: 29459038. PMCID: PMC6026051.
  74. Porrello A, Leslie PL, Harrison EB, Gorentla BK, Kattula S, Ghosh SK, Azam SH, Holtzhausen A, Chao YL, Hayward MC, Waugh TA, Bae S, Godfrey V, Randell SH, Oderup C, Makowski L, Weiss J, Wilkerson MD, Hayes DN, Earp HS, Baldwin AS, Wolberg AS, Pecot CV. Nat Commun. 2018 May 18;9(1):1988. doi: 10.1038/s41467-018-04355-w. PMID: 29777108. PMCID: PMC5959879.
  75. Terryah ST, Fellner RC, Ahmad S, Moore PJ, Reidel B, Sesma JI, Kim CS, Garland AL, Scott DW, Sabater JR, Carpenter J, Randell SH, Kesimer M, Abraham WM, Arendshorst WJ, Tarran R. Am J Physiol Lung Cell Mol Physiol. 2018 Jan 1;314(1):L192-L205. doi: 10.1152/ajplung.00546.2016. PMID: 28982737. PMCID: PMC5866433.
  76. Yu D, Saini Y, Chen G, Ghio AJ, Dang H, Burns KA, Wang Y, Davis RM, Randell SH, Esther Jr CR, Paulsen F, Boucher RC. Am J Pathol. 2018 Jan;188(1):95-110.doi: 10.1016/j.ajpath.2017.09.016. PMID: 29107074. PMCID: PMC5745530.
  77. Keating JE, Minges JT, Randell SH, Glish GL. Anal Methods. 2018;10(1):46-50. doi: 10.1039/C7AY02204B. PMID: 29568335. PMCID: PMC5858713.
  78. Randell SH, Zeldin DC. Am J Respir Cell Mol Biol. 2017 Dec;57(6):633-634. doi: 10.1165/rcmb.2017-0275ED. PMID: 29192828. PMCID: PMC5800897.
  79. Snyder RJ, Hussain S, Tucker CJ, Randell SH, Garantziotis S. Part Fibre Toxicol. 2017 Nov 13;14(1):44. doi: 10.1186/s12989-017-0225-1. PMID: 29132433. PMCID: PMC5683528.
  80. Venkataraman A, Blackwell JW, Funkhouser WK, Birchard KR, Beamer SE, Simmons WT, Randell SH, Egan TM. Transplant Proc. 2017 Sep;49(7):1678-1681. doi: 10.1016/j.transproceed.2017.04.004. PMID: 28838463. PMCID: PMC6034983.
  81. Fossum SL, Mutolo MJ, Tugores A, Ghosh S, Randell SH, Jones LC, Leir SH, Harris A. J Biol Chem. 2017 Jun 30;292(26):10938-10949. doi: 10.1074/jbc.M117.775304. PMID: 28461336. PMCID: PMC5491778.
  82. Xiang H, Yuan L, Gao X, Alexander PB, Lopez O, Lau C, Ding Y, Chong M, Sun T, Chen R, Liu SQ, Wu H, Wan Y, Randell SH, Li QJ, Wang XF. Cell Discov. 2017 Jun 13;3:17019. doi: 10.1038/celldisc.2017.19. PMID: 28626588. PMCID: PMC5468773.
  83. Gentzsch M, Boyles SE, Cheluvaraju C, Chaudhry IG, Quinney NL, Cho C, Dang H, Liu X, Schlegel R, Randell SH. Am J Respir Cell Mol Biol. 2017 May;56(5):568-574. doi: 10.1165/rcmb.2016-0276MA. PMID: 27983869. PMCID: PMC5449492.
  84. Anthony SJ, Gilardi K, Menachery VD, Goldstein T, Ssebide B, Mbabazi R, Navarrete-Macias I, Liang E, Wells H, Hicks A, Petrosov A, Byarugaba DK, Debbink K, Dinnon KH, Scobey T, Randell SH, Yount BL, Cranfield M, Johnson CK, Baric RS, Lipkin WI, Mazet JA. MBio. 2017 Apr 4;8(2). doi: 10.1128/mBio.00373-17. PMID: 28377531. PMCID: PMC5380844.
  85. Liu X, Krawczyk E, Suprynowicz FA, Palechor-Ceron N, Yuan H, Dakic A, Simic V, Zheng YL, Sripadhan P, Chen C, Lu J, Hou TW, Choudhury S, Kallakury B, Tang DG, Darling T, Thangapazham R, Timofeeva O, Dritschilo A, Randell SH, Albanese C, Agarwal S, Schlegel R. Nat Protoc. 2017 Feb;12(2):439-451. doi: 10.1038/nprot.2016.174. PMID: 28125105.ÌýPMCID: PMC6195120.
  86. Mitchel JA, Antoniak S, Lee JH, Kim SH, McGill M, Kasahara DI, Randell SH, Israel E, Shore SA, Mackman N, Park JA. Am J Respir Cell Mol Biol. 2016 Apr;54(4):524-31. doi: 10.1165/rcmb.2015-0252OC. PMID: 26407210. PMCID: PMC4821058.
  87. Gentzsch M, Ren HY, Houck SA, Quinney NL, Cholon DM, Sopha P, Chaudhry IG, Das J, Dokholyan NV, Randell SH, Cyr DM. Am J Physiol Lung Cell Mol Physiol. 2016 Sep 1;311(3):L550-9. doi: 10.1152/ajplung.00186. PMID: 27402691. PMCID: PMC5142211.
  88. Wagner DE, Cardoso WV, Gilpin SE, Majka S, Ott H, Randell SH, Thébaud B, Waddell T, Weiss DJ; ATS Subcommittee on Stem Cells and Cell Therapies. Ann Am Thorac Soc. 2016 Aug;13(8):S259-78. doi: 10.1513/AnnalsATS.201606-466ST. PMID: 27509163.
  89. Yu D, Davis RM, Aita M, Burns KA, Clapp PW, Gilmore RC, Chua M, O’Neal WK, Schlegel R, Randell SH, C Boucher R. Invest Ophthalmol Vis Sci. 2016 Apr 1;57(4):2328-43. doi: 10.1167/iovs.15-17945. PMID: 27127933. PMCID: PMC4855829.
  90. Menachery VD, Yount BL Jr, Sims AC, Debbink K, Agnihothram SS, Gralinski LE, Graham RL, Scobey T, Plante JA, Royal SR, Swanstrom J, Sheahan TP, Pickles RJ, Corti D, Randell SH, Lanzavecchia A, Marasco WA, Baric RS. Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3048-53. doi: 10.1073/pnas.1517719113. PMID: 26976607. PMCID: PMC4801244.
  91. Park JA, Mitchel JA, Qazvini NT, Kim JH, Park CY, Butler JP, Israel E, Randell SH, Shore SA, Drazen JM, Fredberg JJ. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S102. doi: 10.1513/AnnalsATS.201506-382MG. PMID: 27027941. PMCID: PMC5015726.
  92. Turner MJ, Matthes E, Billet A, Ferguson AJ, Thomas DY, Randell SH, Ostrowski LE, Abbott-Banner K, Hanrahan JW. Am J Physiol Lung Cell Mol Physiol. 2016 Jan 1;310(1):L59-70. doi: 10.1152/ajplung.00324.2015. PMID: 26545902.
  93. Park JA, Kim JH, Bi D, Mitchel JA, Qazvini NT, Tantisira K, Park CY, McGill M, Kim SH, Gweon B, Notbohm J, Steward R Jr, Burger S, Randell SH, Kho AT, Tambe DT, Hardin C, Shore SA, Israel E, Weitz DA, Tschumperlin DJ, Henske EP, Weiss ST, Manning ML, Butler JP, Drazen JM, Fredberg JJ. Nat Mater. 2015 Oct;14(10):1040-8. doi: 10.1038/nmat4357. PMID: 26237129. PMCID: PMC4666305.
  94. Evans ES, Hackney AC, McMurray RG, Randell SH, Muss HB, Deal AM, Battaglini CL. Integr Cancer Ther. 2015 Sep;14(5):436-45. doi: 10.1177/1534735415580681. PMID: 25873292.
  95. Fritzsching B, Zhou-Suckow Z, Trojanek JB, Schubert SC, Schatterny J, Hirtz S, Agrawal R, Muley T, Kahn N, Sticht C, Gunkel N, Welte T, Randell SH, Länger F, Schnabel P, Herth FJ, Mall MA. Am J Respir Crit Care Med. 2015 Apr 15;191(8):902-13. doi: 10.1164/rccm.201409-1610OC. PubMed PMID: 25607238; PubMed Central PMCID: PMC4435455.
  96. Chand HS, Montano G, Huang X, Randell SH, Mebratu Y, Petersen H, Tesfaigzi Y. Nat Commun. 2014 Nov 27;5:5567. doi: 10.1038/ncomms6567. PubMed PMID: 25429397; PubMed Central PMCID: PMC4247165.
  97. Hogan BL, Barkauskas CE, Chapman HA, Epstein JA, Jain R, Hsia CC, Niklason L, Calle E, Le A, Randell SH, Rock J, Snitow M, Krummel M, Stripp BR, Vu T, White ES, Whitsett JA, Morrisey EE. Cell Stem Cell. 2014 Aug 7;15(2):123-38. doi: 10.1016/j.stem.2014.07.012. Review. PubMed PMID: 25105578; PubMed Central PMCID: PMC4212493.
  98. Cholon DM, Quinney NL, Fulcher ML, Esther CR Jr, Das J, Dokholyan NV, Randell SH, Boucher RC, Gentzsch M. Sci Transl Med. 2014 Jul 23;6(246):246ra96. doi: 10.1126/scitranslmed.3008680. PubMed PMID: 25101886; PubMed Central PMCID: PMC4272825.
  99. Chen G, Korfhagen TR, Karp CL, Impey S, Xu Y, Randell SH, Kitzmiller J, Maeda Y, Haitchi HM, Sridharan A, Senft AP, Whitsett JA. Am J Respir Crit Care Med. 2014 Feb 1;189(3):301-13. doi: 10.1164/rccm.201306-1181OC. PubMed PMID: 24392884; PubMed Central PMCID: PMC3977731.
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