Office of Research and Scholarship /healthsciences/research Department of Health Sciences Wed, 28 Aug 2024 19:50:34 +0000 en-US hourly 1 Four PhD Students Received the 2024 DHS Research Excellence Awards /healthsciences/research/four-phd-students-received-the-2024-dhs-research-excellence-awards/ Fri, 26 Jul 2024 14:22:56 +0000 /healthsciences/research/?p=4829 Read more]]> Four PhD students, Orla Putnam, Sayoko Kawabata, Soomin Kim, and Rachana Gangwani, were recently awarded the Department of Health Sciences Research Excellence Awards and presented their work at the Department’s April Research Forum. Each year these awards recognize PhD students in the DHS “who showcase research excellence in their wider academic and professional communities.”

Putnam is a fourth-year PhD candidate in the Speech and Hearing Sciences program. Her research involves characterizing what autism looks like in people who are assigned female at birth using language processing, eye tracking, and qualitative methods. She will use the award funds to support the dissemination of her research by supporting her travel costs to conferences.

“I am so honored to be receiving this award, and it feels wonderful to be recognized for my research,” said Putnam. Once she completes her PhD, Putnam’s goals are to pursue postdoctoral training in language processing and other methods of characterizing communication and establish her own research lab at a university.

Kawabata is a PhD candidate in the Occupational Science program and pursues a research focus on the occupation of play for children and youth in a historically Black neighborhood in Hillsborough, NC. She is conducting ethnographic research in this neighborhood that has experienced many immigrant families moving into its affordable housing.

“I am collaborating with a resident-led community watch group to conduct the study,” said Kawabata. “I am interested in describing and exploring how play for youth in this community is shaped through socio-historical elements and how play contributes to community cohesion.”

She plans to use the funds for research dissemination and to present at various conferences. Kawabata aspires to make use of her expertise in community-based research that she has gained in the program, and bridge that experience with the Japanese occupational science community and the rest of the world.

Gangwani is a fourth-year PhD student in the Human Movement Science program, and her research focuses on using multi-modal neuroimaging techniques to develop brain-based measures in individuals with neurological conditions across the lifespan. After completing her PhD, she hopes to secure a postdoctoral position to develop her expertise in neuroscience and neurorehabilitation.

“I’m thrilled and deeply appreciative to have received this award,” said Gangwani. “This recognition motivates me to further my research and academic pursuits, reinforcing my dedication to contributing meaningfully to the field of stroke rehabilitation.” She will use the funds to attend and present for the first time about her dissertation project at the American Society of Neurorehabilitation conference.

Kim is a third-year PhD student in the Division of Speech and Hearing Sciences. She studies aphasia and apraxia of speech, and is interested in discourse-based early differential diagnosis. She has used her funding to attend the Motor Speech Conference in San Diego, where she presented to her peers and colleagues.

“I was so surprised to receive this award – I did not expect to receive it, but at the same time, I was eager to hear back from the committee,” said Kim. “I am so thankful to the committee, my advisors, and myself, too, for persevering with the application.”

Kim’s goal is to better understand acquired neurological communication disorders. She wants to contribute to developing diagnostic methods that are less stressful for people with aphasia yet sensitive to the early differentiation of degenerative diseases.

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Clare Harrop, Dara Chan, and Laura Klinger Awarded Grant to Study Social Connections and Suicidal Thoughts in Older Autistic Adults /healthsciences/research/clare-harrop-dara-chan-and-laura-klinger-awarded-grant-to-study-social-connections-and-suicidal-thoughts-in-older-autistic-adults/ Wed, 07 Feb 2024 21:29:21 +0000 /healthsciences/research/?p=4789 Read more]]> Clare Harrop, PhD, Dara Chan, ScD, CRC, and Laura Klinger, PhD, are recipients of a National Institute of Mental Health (R21) grant, allowing them to study the associations between social connections and suicidal thoughts and behaviors in older adults with autism.

NIMH R21 grants support the early stages of exploratory and developmental research. According to the NIMH, these studies are considered high-risk but with the potential to lead to breakthroughs and make significant impacts in the area of the research.

“Our team has been working to understand various risk factors for suicidal thoughts and behaviors in autism,” said Harrop. “Suicide is the leading cause of death in autism and a major public health issue.” While there is an increased risk for individuals with autism to think about and die by suicide, it remains an overlooked crisis that the team is studying with hopes to change.

Project Details

Harrop and her team became interested in the grant as it related directly to some of their existing research. “The National Institute of Mental Health announced funding opportunities related to social disconnection and suicide in older adults around the time we started our (Organization for Autism Research) and it seemed too good an opportunity to not apply to it,” said Harrop.

In this fully remote study, the team plans to recruit 65 older adults, including 40 with an autism diagnosis. The participants will be asked to complete a series of surveys about their social connections (in person and online) and community activities and attend a clinical interview on Zoom, which will address topics such as suicidal thoughts and behaviors.

In addition, the participants will wear GPS trackers for a week that will allow the team to record the locations in which they are traveling in the community, their resource utilization, and their time spent away from home. Subsequently, a second Zoom interview with the team will be conducted to discuss their community activities and social connections collected from the GPS data.

“Our goal is to use this mixed methods data to understand how different sources of social disconnection serve as potential risk factors for suicidal thoughts and behaviors in older adults,” said Harrop. “We hope the data will provide actionable areas for which we can begin to develop effective and scalable interventions for this vulnerable population.”

Furthermore, Harrop explains that the study will “examine potential sex and gender differences in social connections as a protective factor for suicidal thoughts and behaviors in older autistic and non-autistic adults.”

Harrop and her team hope the project will expand the body of knowledge related to suicide prevention and intervention by improving their understanding of suicide risk in older adults with autism.

About the Research Team

Harrop is an assistant professor within the Department of Health Sciences’ Office of Research and Scholarship and the TEACCH Autism Program. Throughout her research, she has focused on using various methods to understand the sex differences in individuals with a diagnosis of autism.

Chan is an associateprofessor and admissions chair in the Department of Health Sciences’ Division of Clinical Rehabilitation and Mental Health Counseling. Her research interests include utilizing global positioning systems (GPS) and geographic information systems (GIS) to understand and measure community participation and integration, and resource utilization.

Klinger is an associate professor in the Department of Psychiatry and the director of the TEACCH Autism Program. She is a clinical psychologist committed to community-based care and methods to support the implementation of evidence-based practices in community settings. Her current research is focused on identifying and supporting service needs for individuals from young adulthood through aging.

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Racial Disparities in Hospitalization due to Ambulatory Care Sensitive Conditions among U.S. Children with Autism /healthsciences/research/racial-disparities-in-hospitalization-due-to-ambulatory-care-sensitive-conditions-among-u-s-children-with-autism/ Thu, 13 Jul 2023 18:35:48 +0000 /healthsciences/research/?p=4768 Read more]]> The prevalence of autism spectrum disorder (ASD) has increased dramatically in recent years and affects every race, ethnicity, and socioeconomic status; thus, it requires an adequate and integrated system that supports quality primary care and health equity. Hospitalization for ambulatory care sensitive conditions (ACSCs) has been examined extensively as an indicator of the accessibility and overall effectiveness of primary health care. Families of children with ASD may experience more stress related to unmet primary care needs that may lead to potentially avoidable hospitalizations for ACSCs. Among children with ASD, Hispanics and non-Hispanic Blacks are less likely than non-Hispanic Whites to have a usual source of care and to have had recommended preventive treatments. Little is known about associations between race/ethnicity and preventable hospitalization for ACSCs among children with ASD.

This study compared ACSCs hospitalization patterns and outcomes among autistic children nationally by race/ethnicity and income level. Using secondary data from the US Nationwide Inpatient Sample (NIS), we conducted multivariable regression analyses to determine the potential effect of race and income level on the likelihood of inpatient stays for ACSCs among autistic children after controlling demographic and clinical characteristics.

Our results highlight the existing racial/ethnic and income disparities in preventable hospitalization among underserved children. Racial minority and children from low-income family have poorer primary care experiences and have higher risk of preventable hospitalizations for ACSCs. Inequities of access to health care among racial/ethnic minorities were most notable for autistic children with chronic preventable conditions. Specifically, the burden of asthma hospitalization falls disproportionally on autistic children of Black race. ASD disparities and inequities of access to health care among racial/ethnic groups persist. Some hospitalizations may be avoided through better primary care and chronic disease management such as improving parent and provider communication for adherence to asthma medications.

Clinical and social programs, policies and interventions need to be aimed at ensuring the availability of and accessibility to quality primary care for low-income Hispanic and Black children with ASD and mitigating health inequities associated with potentially avoidable hospitalization.

Contact for more information:
Wanqing Zhang
Research Methodologist
Assistant Professor
3003 Bondurant Hall
CB #7122

Email: wanqing_zhang@med.unc.edu
Office phone: (919) 962-4069

Principal Investigators:
Wanqing Zhang, PI
Linda Watson, Co-I
Khalilah Johnson, Co-I

Lead Principal Investigators:
Wanqing Zhang

Primary Funding Source:
Health Resources and Services Administration (HRSA)

Project Start Date:
September 1, 2021

Project End Date:
August 31, 2023

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2022 DHS Research and Scholarship Report /healthsciences/research/2022-dhs-research-and-scholarship-report/ Thu, 01 Jun 2023 15:43:59 +0000 /healthsciences/research/?p=4764 The 2022 Department of Health Sciences Research and Scholarship Annual Report is now available for public viewing. Learn more about our accomplishments from the past year, including cross-campus collaborations, faculty publications and areas of research focus.

View the report:

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Spectrum Names Dr. Clare Harrop a Top 40 Under 40 Rising Star for Autism Research https://www.spectrumnews.org/news/40-under-40/#new_tab Fri, 20 Jan 2023 14:46:12 +0000 /healthsciences/research/?p=4741 Spectrum, the leading source of news and expert opinion on autism research, has named Dr. Clare Harrop, Assistant Professor in the Department of Health Sciences, as one of the top 40 Under 40 rising stars for autism research. Harrop is a member of the Autism Center and an Investigator at the Frank Porter Graham Child Development Institute. She is affiliated with the Carolina Institute for Developmental Disabilities and faculty in the DHS Office of Research and Scholarship.

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Khalilah Johnson (’16 PhD) Receives Robert Wood Johnson Foundation Health Equity Scholars for Action Award /healthsciences/ocsci/khalilah-johnson-16-phd-receives-robert-wood-johnson-foundation-health-equity-scholars-for-action-award/#new_tab Tue, 23 Nov 2021 15:29:13 +0000 /healthsciences/research/?p=4691 Dr. Khalilah Johnson has received the Robert Wood Johnson Foundation Health Equity Scholars for Action award. Johnson is an assistant professor in the Division of Occupational Science and Occupational Therapy in the Department of Allied Health Sciences in the .

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Clare Harrop Receives 5-Year NIH Award to Study Sex-Specific Trajectories in Autism Spectrum Disorder /healthsciences/research/clare-harrop-receives-5-year-nih-award-to-study-sex-specific-trajectories-in-autism/ Mon, 25 Oct 2021 14:16:49 +0000 /healthsciences/research/?p=4675 Read more]]> Clare Harrop, Assistant Professor in the Department of Allied Health Sciences, has received a 5-year, $3.28 million R01 award from the NIH () to chart the impact of assigned sex at birth on developmental trajectories in young autistic children. The objective of the project is to characterize how development in autism varies by assigned sex with the goal of informing future sex-sensitive screening protocols and providing evidence for sex- and gender-sensitive interventions that better address the needs of autistic females.

“Autism is diagnosed at a rate of four males to one female, so we know considerably less about the profiles and trajectories of autistic females,” says Harrop. “However, there is a growing consensus that females are underdiagnosed and understudied, potentially due to differences in how autism presents in females. What we do know comes from small, single time-point studies which prevent our understanding of how autistic males and females may differ over time and during different developmental periods.”

Harrop, with University of North Carolina – Chapel Hill collaborators (Psychology and Neuroscience), Heather Hazlett (Psychiatry) and Rebecca Grzadzinski (Psychiatry), will study the developmental trajectories of young autistic females and males, as well as non-autistic peers, using multiple methods within an accelerated longitudinal design.

“Such a design allows us to extend our previous findings to a larger sample and provide a novel way to chart development in harder to reach groups, such as autistic females,” says Harrop.

The project will also collaborate with (Children’s National Hospital) to study how gender impacts development, and with (Children’s Hospital of Philadelphia) to chart the emergence of camouflaging behaviors in autism.

Young girl doing eye tracking exercise

“Autistic youth and adults are more likely to experience gender diversity than non-autistic youth. But no study has charted the early development of gender in autism,” says Harrop. “Additionally, autistic individuals, particularly females, are more likely to employ certain behaviors, such as making eye contact or small talk, to mitigate some of their day-to-day challenges. We know this can have profound downstream effects on mental health.”

Harrop’s project builds on her previous work funded by the Autism Science Foundation and a . She and her team will begin recruitment for the study in early 2022.

“We are incredibly excited to start this research. Our goal for a number of years has been to recruit and follow a large, longitudinal cohort of females through key developmental periods. This is the first stage and we hope to extend our work to non-binary youth in the future. We hope this work can contribute in meaningful ways to the lives of autistic females and their families.”

Clare Harrop, PhD is an Assistant Professor and Translational Research Methodologist within the Department of Allied Health Sciences Office of Research and Scholarship.

Daniel Bauer, PhD is a Professor and Director of the Quantitative Psychology Program and L.L. Thurstone Psychometric Laboratory of the Department of Psychology and Neuroscience.

Heather Hazlett, PhD is an Assistant Professor in the Department of Psychiatry at Hospitals – Chapel Hill.

Rebecca Grzadzinski, PhD is an Assistant Professor in the Department of Psychiatry at the Carolina Institute for Developmental Disabilities.

 

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Hospitalizations for Pediatric Opioid Use Disorders: Exploring Racial Disparities among US regions /healthsciences/research/hospitalizations-for-pediatric-opioid-use-disorders-exploring-racial-disparities-among-us-regions/ Tue, 25 May 2021 17:40:22 +0000 /healthsciences/research/?p=3666 Read more]]> Zhang ProjectExposure to prescription opioids in the pediatric population is an important public health concern. Opioid hospitalizations among US children and adolescents have doubled in the last decade. There is an urgent need to better characterize the opioid epidemic in all pediatric populations, across different racial groups and regions in the United States. However, research on pediatric opioid use disorders (OUD) and health disparities has been sparse. This proposed study intends to fill this research gap through two specific aims: 1) to compare hospitalization patterns and outcomes among pediatric OUD nationally by race/ethnicity and US region, and 2) to investigate how race and region are associated with variations in hospital care and subsequent clinical outcomes for pediatric patients with OUD, and whether these two factors interact. We will pool three years of the most recent US Nationwide Inpatient Sample (NIS), a database maintained by the Agency for Healthcare Research and Quality as a part of the Healthcare Cost and Utilization Project. We are interested in determining whether racial disparities in hospital use and discharge outcomes exist among US regions for pediatric patients with OUD. Separate sets of regression models will be developed for each hospitalization outcome by examining univariate and multivariate associations with race and region. The proposed study will provide insight into the development of potential measures for comparison in future studies to assess underlying geographic disparities and racial differences simultaneously. Hospitalization is a key component of the continuum of care for children and adolescents with complex health problems, including psychiatric and substance use disorders. Examining the effect of race and region in inpatient hospital care could inform policy and practice and lead to the development of specific and culturally congruent clinical and programmatic strategies. This proposal is unique in its use of the largest national dataset to study racial differences in the utilization of inpatient services for children and adolescents with OUD across the four US Census Bureau–defined regions. Findings will contribute to more informed policy and practice regarding this ongoing US public health crisis, while addressing the unique health care needs of different racial groups across regions.

 

View Project Poster

Contact for more information:
Wanqing Zhang
Research Methodologist
Assistant Professor
3003 Bondurant Hall
CB #7122

Email: wanqing_zhang@med.unc.edu
Office phone: (919) 962-4069

Principal Investigators:
Wanqing Zhang, PhD, (PI)
Paul Chelminski, MD, (Co-I)
Doré LaForett, PhD, (Co-I)
Kelsey Thompson, MS, (RA)

Lead Principal Investigators:
Wanqing Zhang

Primary Funding Source:
Maternal and Child Health Bureau

Secondary Funding:
Health Resources and Services Administration (HRSA)

Project Start Date:
July 1, 2019

Project End Date:
June 30, 2021

Institutions Involved:
Frank Porter Child Development Institute (FPG)

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Departments of Allied Health Sciences and Neurology Announce Nicole Short, PhD, as the 2020-2021 Sleep Innovative Research Grant Recipient /healthsciences/2021/01/unc-school-of-medicine-departments-of-allied-health-sciences-and-neurology-announce-nicole-short-phd-as-the-2020-2021-sleep-innovative-research-grant-recipientthe-departments-of-allied-health-scienc/#new_tab Fri, 22 Jan 2021 20:29:47 +0000 /healthsciences/research/?p=4643 TheDepartments of Allied Health Sciences(DAHS) Office of Research and Scholarship andNeurologyhave awarded Nicole Short, an assistant professor in the Department of Anesthesiology, with its 2020-2021 Sleep Innovative Research (SIRG) grant.

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Disparities in Health Care Access and Utilization of Children during Autism Insurance Reform /healthsciences/research/disparities-in-health-care-access-and-utilization-of-children-during-autism-insurance-reformdisparities-in-health-care-access-and-utilization-of-children-during-autism-insurance-reform/ Wed, 16 Dec 2020 18:40:34 +0000 /healthsciences/research/?p=4639 Read more]]> The prevalence of autism spectrum disorder (ASD) has increased rapidly in recent years. At the same time, comprehensive ASD insurance reform laws have been enacted through legislation or administrative mandates in most US states since 2006. Legislation targeted toward private insurance was designed to facilitate access to and coverage of integrated medical and behavioral health services, and can be beneficial to children with ASD who have an unmet need for services. However, research on factors contributing to access and utilization disparities in the US pediatric population during autism insurance reform has been sparse. This proposed study intends to fill this gap through two specific aims: 1) identify the determinants that contribute to disparities in healthcare access and utilization among children with ASD by early and late policy adopting states, and 2) investigate potential changes in hospitalization patterns for children with ASD, prior to and following comprehensive ASD insurance reform. We will use two national representative datasets, the National Survey of Children’s Health (NSCH) sponsored by the Maternal and Child Health Bureau of the Health Resources and Services Administration, and Kids’ Inpatient Database (KID) sponsored by the Healthcare Cost and Utilization Project of the Agency for Healthcare Research and Quality, to accomplish the specific aims of this proposed study. Separate sets of regression models will be developed to examine disparities in health services utilization in children with ASD in order to assess the potential impact of ASD insurance reform associated with various health services. Disparities may affect some groups more than others as ASD insurance reform continues undergo changes. Examination of these disparities is essential to understanding the type of changes needed to better-inform policy, in an effort to reduce disparities among underserved and disadvantaged children and families. The results will provide insight for future studies into potential measures of comparison needed to assess the impact of health care coverage changes on health services utilization.

Researchers

  • Wanqing Zhang, PI
  • Linda Watson, Investigator
  • Doré LaForett, Investigator
  • Kelsey Thompson, Research Assistant
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