黑料网

The title of the article, published in PNAS, is “Lack of pairing during meiosis triggers multigenerational transgene silencing in Caenorhabditis elegans.” Co-first authors are Luciana Leopold, a graduate student in the Curriculum in Genetics and Molecular Biology, and Bree Heestand, a postdoctoral fellow in Shawn’s lab. This silencing process can...

Bailey Peck, a Genetics and Molecular Biology graduate student in Praveen Sethupathy’s lab, is first author of a collaborative paper, with Bioinformatics and Computational Biology grad student Matthew Weiser (Furey lab), Shehzad Sheikh, Assistant Professor of Medicine and Genetics (senior author), and Drs. Sethupathy and Furey as coauthors. The article...

Jim was one of four discussants on NPR’s “On Point” and coauthor of an editorial in JAMA The “On Point” discussion, related to President Obama’s announcement regarding the Precision Medicine Initiative, is available as a podcast. In the JAMA Viewpoint article, Jim and Michael Watson of the ACMG Foundation for...

The title of the paper is “Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C.” Sara is a BCB graduate student who is co-mentored by Praveen Sethupathy and Stan Lemon (Department of Medicine). In this study, Selitsky et al. identify for the first...

Matt Weiser, a graduate student in Terry’s lab, is first author on the paper, entitled “Novel Distal eQTL Analysis Demonstrates Effect of Population Genetic Architecture on Detecting and Interpreting Associations.” Standard eQTL mapping methods carry significant multiple testing burdens, limiting their ability to detect eQTL distal to the affected gene....

Shawn and Eric Miska at the University of Cambridge are senior authors on the paper, and Shawn’s former postdoc, Aisa Sakaguchi, and former graduate student, Matt Simon, as co-first authors with Peter Sarkies from Dr. Miska’s lab. This study establishes a role for small RNAs in promoting transgenerational fertility via...

Fernando will serve a three-year term beginning January 1, 2015. See the official announcement on the GSA web site. The GSA is the professional membership organization for scientific researchers and educators in the field of genetics, with over 5,000 members. Society members work to advance knowledge in the basic mechanisms...

Yun Li, Karen Mohlke, and Chuck Perou are among the top 1% most cited world researchers in their subject fields for 2014. Thomson Reuters has listed Yun and Karen among the most highly cited in Molecular Biology & Genetics and Chuck in Clinical Medicine. To see the complete list and...

Evans and Perou are quoted regarding the risks of reporting germline mutations in numerous genes implicated in rare forms of hereditary predispositions to breast cancer. Chuck points out that there are probably 10 – 100 genes in addition to BRCA1 and BRCA2 that may contribute to breast cancer susceptibility. Both...

The article discusses three reports on DNA variants in the human genome that affect gene regulation epigenetically, via sequence-specific binding-affinity of transcription factors.