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Department of Genetics Publications August 20 – Sept. 2, 2017

September 5, 2017
Department of Genetics faculty and collaborators published eleven papers between August 20 and September 2, 2017. Genetic architecture of atherosclerosis dissected by QTL analyses in three F2 intercrosses of apolipoprotein E-null mice on C57BL6/J, DBA/2J and 129S6/SvEvTac backgrounds. Makhanova N, Morgan AP, Kayashima Y, Makhanov A, Hiller S, Zhilicheva S,...

Department of Genetics Publications for Aug 6 – Aug 19, 2017

August 23, 2017
Department of Genetics faculty and collaborators published twelve papers between August 6 and August 19, 2017. Upregulation of autophagy genes and the unfolded protein response in human heart failure. Jensen BC, Bultman SJ, Holley D, Tang W, de Ridder G, Pizzo S, Bowles D, Willis MS. Int J Clin Exp...

Thanks to a ºÚÁÏÍø research project, she can walk again

August 15, 2017
As ºÚÁÏÍø geneticist Jonathan Berg gears up to lead a $9.7-million renewal of the NCGENES project, we look at a story from the original study and how it changed the fortunes of a woman from Goldsboro, NC. CHAPEL HILL, NC – When she was six, a mysterious ailment caused Elizabeth...

Time + Tenacity: The Cure Code

July 20, 2017
Endeavors, the ºÚÁÏÍø-Chapel Hill publication focused on research and creative activity, has published a feature article this month that describes the inception and growth of the Department of Genetics. When Fred Sanger figured out how to sequence DNA in 1975, the world changed – and so did ºÚÁÏÍø. As more...

Department of Genetics Publications for June 25 – July 8, 2017

July 10, 2017
Department of Genetics faculty and collaborators published thirteen papers during the past two weeks. Patterns of cell cycle checkpoint deregulation associated with intrinsic molecular subtypes of human breast cancer cells. Bower JJ, Vance LD, Psioda M, Smith-Roe SL, Simpson DA, Ibrahim JG, Hoadley KA, Perou CM, Kaufmann WK. NPJ Breast...

Newly designed viral vectors could lead to improved gene therapies

June 29, 2017
ºÚÁÏÍø and University of Florida researchers created viruses to deliver gene therapies while evading pre-existing immune system responses. Aravind Asokan, PhD, led the research team at ºÚÁÏÍø. June 15, 2017 CHAPEL HILL, NC – For many patients, participating in gene therapy clinical trials isn’t an option because their immune system...

Journal Edited by ºÚÁÏÍø Researcher Reaches Record High Impact Factor

June 29, 2017
ACMG’s Genetics in Medicine journal receives record high impact factor, is now in top 2.5 percent of all indexed journals. The American College of Medical Genetics and Genomics (ACMG) announced that the Thomson Reuters Impact Factor Journal Citation Reports has just increased the impact factor of the ACMG’s peer-reviewed medical...

Department of Genetics Publications for June 10-24, 2017

June 26, 2017
Department of Genetics faculty and collaborators published twelve papers during the past two weeks. Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B,...

Yuchao Jiang, PhD, Appointed Assistant Professor in Department of Biostatistics with Joint Appointment in Department of Genetics

June 23, 2017
Dr. Jiang’s primary research interests lie in statistical modeling, method development and data analysis in genetics and genomics. Dr. Jiang’s primary research interests lie in statistical modeling, method development and data analysis in genetics and genomics. Dr. Jiang has a primary appointment in Biostatistics and a joint appointment in Genetics....

President Trump intends to appoint ºÚÁÏÍø Lineberger’s Norman Sharpless as National Cancer Institute director

June 14, 2017
President Trump announced he intends to appoint ºÚÁÏÍø Linebarger’s Norman E. (Ned) Sharpless as the National Cancer Institute director. Dr. Sharpless is the Director of the ºÚÁÏÍø Lineberger Comprehensive Cancer Center, the Wellcome Distinguished Professor of Cancer Research, and joint Professor in the Department of Genetics. June 10, 2017 CHAPEL...