Dr. Alex Rubinsteyn (Associate Professor, Genetics) was awarded a new grant from the Jaime Leandro Foundation for his project titled 鈥淥ptimization of personalized cancer immunotherapeutic approaches鈥�.
The project is focused on three aims: 1) Computational biology (LENS, TCRSift, EXACTO, and MHCFlurry development and packaging; 2) Experimental biology (optimization of flow cytometry panels for advanced immune monitoring, assay for assessing antigen specific T cell function, and method optimization to discover antigen specific CD8+ T cells; 3) Discovery science (focused on optimal vaccine formulation and timing of neoantigen vaccination and TCR-T therapy.