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Focused Ultrasound Thalamotomy for the Prevention of Secondary Generalization in Focal Onset Epilepsy

This study will assess the safety and feasibility of MRI-guided focused ultrasound in patients with epilepsy who have become resistant to medications. This study is for adult patients with refractory, partial-onset epilepsy with secondary generalization. Patients enrolled in this study will be selected from patients being cared for by the epilepsy program at the University of North Carolina at Chapel Hill, or referred from elsewhere to enroll in the study. 


3-D Tractography FUS Ablation for Essential Tremor

This study is for patients with essential tremor and will evaluate focused ultrasound ablation with the support of 3-D tractography, a neuroimaging technique to visually represent nerve tracts within the brain. 


Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With Glioblastoma Brain Tumor

This is a prospective, multi-center, pivotal clinical trial to evaluate the safety and efficacy of targeted blood brain barrier disruption in patients with suspected glioblastoma brain tumors. The study will be conducted at up to 25 centers in the US.


SONOBIRD Clinical Study

ºÚÁÏÍø is now enrolling patients in the multicenter, multinational SONOBIRD phase III clinical trial. The clinical trial evaluates the use of a device called SonoCloud®, which can more effectively deliver chemotherapy through the brain to treat malignant brain tumors. This study is open to glioblastoma patients with their first recurrence. The clinical trial at ºÚÁÏÍø Health is led by neurosurgical oncologist, Dr. Dominique Higgins.

For questions about the study or eligibility, please email Camisha Johnson at camisha_johnson@med.unc.edu or call 919-445-4847.