Children's Research Institute /childrensresearch/ “Transforming Care and Inspiring Hope for all children…” Wed, 05 Mar 2025 19:16:59 +0000 en-US hourly 1 Burks and Keet Publish Editorial on Oral Immunotherapy for High Threshold Peanut Allergy https://news.unchealthcare.org/2025/02/burks-and-keet-publish-editorial-on-oral-immunotherapy-for-high-threshold-peanut-allergy/#new_tab Wed, 05 Mar 2025 19:16:59 +0000 /childrensresearch/?p=6281 Wesley Burks, MD, CEO of Health and dean of the , professor of pediatrics, Division of Pediatric Allergy/Immunology, Department of Pediatrics and Corinne A. Keet, MD, PhD, professor of pediatrics, Division of Pediatric Allergy/Immunology, Department of Pediatrics, write editorial in New England Journal of Medicine Evidence titled, “To Eat or Not to Eat: Oral Immunotherapy for High Threshold Peanut Allergy.”

Managing peanut allergy with oral immunotherapy can improve quality of life.

]]> PCORI Awards Researcher $14.4 Million to Study Emerging Medications for PIBD Patients https://news.unchealthcare.org/2024/12/pcori-awards-unc-researcher-14-4-million-to-study-emerging-medications-for-pibd-patients/#new_tab Thu, 05 Dec 2024 21:09:02 +0000 /childrensresearch/?p=6186 The Patient-Centered Outcomes Research Institute (PCORI) announced funding totaling $14.4 million for a Duke- research collaboration to study new treatment options for pediatric inflammatory bowel diseases (PIBD). Michael D. Kappelman, MD, MPH, professor of pediatrics and epidemiology at the , will serve as principal investigator.

The Patient-Centered Outcomes Research Institute (PCORI) announced the approval of funding totaling $14.4 million to study new treatment options for pediatric inflammatory bowel diseases (PIBD).

]]> Researchers to Accelerate Mapping of Cells Crucial to Child Respiratory Health and Disease https://news.unchealthcare.org/2024/12/unc-researchers-to-accelerate-mapping-of-cells-crucial-to-child-respiratory-health-and-disease/#new_tab Thu, 05 Dec 2024 21:08:20 +0000 /childrensresearch/?p=6184 A research project co-led by James Hagood, MD, professor of pediatrics at the , and colleagues will be supported in creating an atlas of the cells and cellular interactions in the nasal and oral cavities, throat, and lower airways of pediatric populations in unprecedented detail.

Scale Biosciences announced the winning projects of the 100 Million Cell Challenge, a research initiative that aims “to push the boundaries of single cell genomics research by encouraging large-scale projects across diverse biological systems.” The projects were selected based on their ability to address critical challenges in global health through global health equity, disease characterization, cancer biology, or therapeutic intervention.

]]> Kappelman Leads Landmark Study Revealing That 100,000 American Youth Are Living with Inflammatory Bowel Disease https://news.unchealthcare.org/2024/11/kappelman-leads-landmark-study-revealing-that-100000-american-youth-are-living-with-inflammatory-bowel-disease/#new_tab Mon, 25 Nov 2024 22:16:16 +0000 /childrensresearch/?p=6173 A comprehensive analysis published in the journal Gastroenterology and led by Michael D. Kappelman, MD, MPH, at the , reveals that U.S. pediatric IBD rates have increased, ranking among the highest globally.

A groundbreaking study published today in Gastroenterology provides the most comprehensive assessment to date of pediatric inflammatory bowel disease (IBD) prevalence in the United States. Funded by the Centers for Disease Control and Prevention (CDC), the research led by Michael D.

]]> Asthma Project Led by Hernandez et al Is One of Two Studies Awarded $1 Million by Novant Health /marsicolunginstitute/asthma-project-led-by-hernandez-et-al-is-one-of-two-studies-awarded-1-million-by-novant-health/#new_tab Fri, 25 Oct 2024 02:02:26 +0000 /childrensresearch/?p=6153 Novant Health has announced that it has, in collaboration with Health and the , awarded $1million to launch two clinical trials in North Carolina. One of the trials, co-led by Michelle Hernandez, MD, aims to reduce “health disparities for children with asthma.”

Continue reading Asthma Project Led by Hernandez et al Is One of Two Studies Awarded $1 Million by Novant Health at Children's Research Institute.

]]> A New Therapy to Prevent or Delay Type 1 Diabetes Now Available at Children’s Hospital https://news.unchealthcare.org/2024/10/a-new-therapy-to-prevent-or-delay-type-1-diabetes-now-available-at-unc-childrens-hospital/#new_tab Fri, 25 Oct 2024 02:00:29 +0000 /childrensresearch/?p=6150 Nina Jain, MD, MBA, professor of pediatric endocrinology, and Ali Calikoglu, MD, retired professor of pediatrics, both at the , played a pivotal role in getting this therapy to the bedside, from assisting with clinical trials to the infusion of the first pediatric patient in North Carolina at Children’s.

A diagnosis of Type 1 diabetes can have a profound impact on a child’s life.

This autoimmune condition occurs when the body’s own immune cells attack the cells that produce insulin, a crucial hormone that regulates blood sugar in the body.

]]> Are Biologics the Future of Food Allergy Treatment? One Study Weighs Pros and Cons https://news.unchealthcare.org/2024/10/are-biologics-the-future-of-food-allergy-treatment-one-study-weighs-pros-and-cons/#new_tab Fri, 25 Oct 2024 01:59:47 +0000 /childrensresearch/?p=6148 Publishing in Annals of Allergy, Asthma and Immunology, researchers delve into the perspectives of community and academic providers on the role of biologics and food allergy. This study was led by co-authors Edwin Kim, MD, Division Chief of Pediatric Allergy and Immunology, and Jill Fisher, PhD, professor in the Department of Social Medicine and Center for Bioethics.

New treatment options are revolutionizing ways to manage and reduce the effects of food allergy.

]]> Selected as Site for New Food Allergy Research https://news.unchealthcare.org/2024/07/unc-school-of-medicine-selected-as-site-for-new-food-allergy-research/#new_tab Tue, 06 Aug 2024 21:05:49 +0000 /childrensresearch/?p=6103 The site lead investigators are Edwin Kim, MD, associate professor of medicine, division chief of Pediatric Allergy & Immunology, and Corinne Keet, MD, PhD, professor of pediatrics, vice chair of clinical and translational research.

]]> Eveline Wu Wins CARRA-Arthritis Foundation Advancing Biosample Collection Award https://news.unchealthcare.org/2024/07/eveline-wu-wins-carra-arthritis-foundation-advancing-biosample-collection-award/#new_tab Tue, 06 Aug 2024 21:04:51 +0000 /childrensresearch/?p=6101 Eveline Wu, MD, MSCR, Associate Professor and Division Chief of Pediatric Rheumatology in the Department of Pediatrics, is one of 14 researchers nationwide selected to receive the award this year.

]]> Leads $9.3-Million Study to Create Chlamydia Vaccine https://news.unchealthcare.org/2024/05/unc-school-of-medicine-leads-9-3-million-study-to-create-chlamydia-vaccine/#new_tab Tue, 04 Jun 2024 18:32:14 +0000 /childrensresearch/?p=6067 This five-year grant from the National Institute of Allergy and Infectious Diseases is led by Toni Darville, MD, director of the Children’s Research Institute, in collaboration with scientists at Vaxcyte, Inc. and the University of Chicago.

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