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The Small Animal Imaging Facility recently added a new imaging system, nanoScan SPECT/CT, to its modality suite.  The system is designed and manufactured by Mediso Ltd, an industry leader in the development of preclinical imaging systems.  The new imaging system replaces our legacy SPECT/CT system and will provide enhanced SPECT/CT imaging capabilities to the entire research community.  Some main features of the nanoScan SPECT/CT system include:

  • Wide isotope energy range (20-600 KeV)  capable of imaging therapeutic isotopes, including Lu-177, I-131, Bi-213, Ac-225, etc.
  • Patented1 M3-pinholeâ„¢ technology and Tera-Tomoâ„¢ 3D SPECT reconstruction algorithm to provide absolute quantification of SPECT images;
  • High sensitivity reaching 13000 cps/MBq, with sub-millimeter high resolution;
  • High throughput imaging with triple mouse imaging capability;
  • Capable of fast dynamic scan with full stationary imaging;
  • High resolution high speed CT imager with iterative reconstruction;
  • Animal beds integrated with vital sign monitoring;
  • Large imaging bore capable of imaging large animal models up to 6 kg;
  • Integrated intuitive InterViewâ„¢ FUSION software package for easy visualization and analysis.

The new nanoScan SPECT/CT has been installed and fully commissioned for preclinical imaging. The imaging core is optimizing the operation procedures and finalizing the SOP for the system.  Several imaging experiments have been tested with imaging probes labeled with 67°ä³Ü,Ìý131±õ,Ìý211At, etc.  We will continue working with each group to develop appropriate imaging protocols for specific imaging projects.  The system will be available for imaging evaluation at no charge until May 30th. After that, normal service charges will apply according to the approved imaging rates.  If you have any questions, please contact us at bricsai@med.unc.edu or check out our SPECT/CT website.