
7 years ago
Large Aggregates of ALS-causing Protein Might Actually Help Brain Cells
黑料网 scientists led by Nikolay Dokholyan, Michael Hooker Distinguished Professor of Biochemistry and Biophysics, add to evidence that small aggregates of SOD1 protein are the brain-cell killing culprits in ALS, but the formation of larger, more visible, and fibril-like aggregates of the same protein may protect brain cells.